Hypoxic regulation of glutamine metabolism through HIF1 and SIAH2 supports lipid synthesis that is necessary for tumor growth. - Wikidata - awgldk - TriplyDB

Hypoxic regulation of glutamine metabolism through HIF1 and SIAH2 supports lipid synthesis that is necessary for tumor growth.

Hypoxic regulation of glutamine metabolism through HIF1 and SIAH2 supports lipid synthesis that is necessary for tumor growth.

http://www.wikidata.org/entity/Q37576769

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Aberrant Lipid Metabolism Promotes Prostate Cancer: Role in Cell Survival under Hypoxia and Extracellular Vesicles Biogenesis Targeting the hypoxic fraction of tumours using hypoxia-activated prodrugs Hypoxia and metabolic adaptation of cancer cells Oncogenes strike a balance between cellular growth and homeostasis Hypoxia signaling pathways: modulators of oxygen-related organelles Broad targeting of angiogenesis for cancer prevention and therapy Metabolic and hypoxic adaptation to anti-angiogenic therapy: a target for induced essentiality Caveolin-1 in the regulation of cell metabolism: a cancer perspective Lipid Droplets: A Key Cellular Organelle Associated with Cancer Cell Survival under Normoxia and Hypoxia Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis Glutamine Ameliorates Mucosal Damage Caused by Immune Responses to Duck Plague Virus.From Krebs to clinic: glutamine metabolism to cancer therapy.The Warburg effect in tumor progression: mitochondrial oxidative metabolism as an anti-metastasis mechanism The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer.CK1δ restrains lipin-1 induction, lipid droplet formation and cell proliferation under hypoxia by reducing HIF-1α/ARNT complex formation Metabolic circuits in neural stem cells.Hypoxia augments outgrowth endothelial cell (OEC) sprouting and directed migration in response to sphingosine-1-phosphate (S1P).ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate.Genome-independent hypoxic repression of estrogen receptor alpha in breast cancer cells.ccmGDB: a database for cancer cell metabolism genes Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A.Hypoxic repression of pyruvate dehydrogenase activity is necessary for metabolic reprogramming and growth of model tumours.Amplification of USP13 drives ovarian cancer metabolism.Heterogeneity in Cancer Metabolism: New Concepts in an Old Field.The role of HIF1α in renal cell carcinoma tumorigenesis.Pheochromocytoma: Gasping for Air.Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach.Reprogramming of glucose, fatty acid and amino acid metabolism for cancer progression.Metabolic changes associated with tumor metastasis, part 2: Mitochondria, lipid and amino acid metabolism.Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions.Metabotropic glutamate receptors in cancer.Measuring the Impact of Microenvironmental Conditions on Mitochondrial Dehydrogenase Activity in Cultured Cells.SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status.Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase.A role for vaccinia virus protein C16 in reprogramming cellular energy metabolism.Oxygen availability and metabolic adaptations.Preclinical Development of a Nontoxic Oral Formulation of Monoethanolamine, a Lipid Precursor, for Prostate Cancer Treatment.The α-ketoglutarate dehydrogenase complex in cancer metabolic plasticity.Hopefully devoted to Q: targeting glutamine addiction in cancer.Normoxic accumulation of HIF1α is associated with glutaminolysis.

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P2860

Hypoxic regulation of glutamine metabolism through HIF1 and SIAH2 supports lipid synthesis that is necessary for tumor growth.

http://www.wikidata.org/entity/Q37576769

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article científic

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article scientifique

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articolo scientifico

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bilimsel makale

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scientific article published on February 2014

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Hypoxic regulation of glutamin ...... is necessary for tumor growth.

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Hypoxic regulation of glutamin ...... is necessary for tumor growth.

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type

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Hypoxic regulation of glutamin ...... is necessary for tumor growth.

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Hypoxic regulation of glutamin ...... is necessary for tumor growth.

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Hypoxic regulation of glutamin ...... is necessary for tumor growth.

@en

Hypoxic regulation of glutamin ...... is necessary for tumor growth.

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J.CMET.2013.11.022

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Cell Metabolism

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Hypoxic regulation of glutamin ...... is necessary for tumor growth.

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Nicholas C Denko

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Ramon C Sun

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P2860

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism

Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells

The hypoxia-controlled FBXL14 ubiquitin ligase targets SNAIL1 for proteasome degradation

Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia

Mammalian alpha-keto acid dehydrogenase complexes: gene regulation and genetic defects

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

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285-292

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scholarly article

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10.1016/J.CMET.2013.11.022

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2

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2014-02-01T00:00:00Z

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