Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs.
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TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8EVER2 protein binds TRADD to promote TNF-α-induced apoptosisOTUB1 modulates c-IAP1 stability to regulate signalling pathwaysNecroptosis in tumorigenesis, activation of anti-tumor immunity, and cancer therapyUbiquitin in the immune systemExpression of GITR Enhances Multiple Myeloma Cell Sensitivity to Bortezomibc-IAP1 and c-IAP2 redundancy differs between T and B cells.Cot/tpl2 participates in the activation of macrophages by adiponectin.Inducing death in tumor cells: roles of the inhibitor of apoptosis proteins.Challenging a Misnomer? The Role of Inflammatory Pathways in Inflammatory Breast CancerIncreased mitochondrial calcium sensitivity and abnormal expression of innate immunity genes precede dopaminergic defects in Pink1-deficient mice.Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding.HOIL-1L interacting protein (HOIP) is essential for CD40 signalingInhibitor of apoptosis proteins (IAPs) and their antagonists regulate spontaneous and tumor necrosis factor (TNF)-induced proinflammatory cytokine and chemokine production.Novel tumor suppressor function of glucocorticoid-induced TNF receptor GITR in multiple myeloma.In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-kappaB and activation of caspase-8Intertwined pathways of programmed cell death in immunity.Cell death in disease: from 2010 onwardsInhibitor of apoptosis proteins as intracellular signaling intermediates.The E3 ubiquitin ligase TRAF6 intercedes in starvation-induced skeletal muscle atrophy through multiple mechanismsTWEAK and TRAF6 regulate skeletal muscle atrophy.Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitinationThe dual functions of receptor interacting protein 1 in fas-induced hepatocyte death during sepsis.TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1TRAF molecules in cell signaling and in human diseasesRegulation of Apoptosis by Inhibitors of Apoptosis (IAPs)T-cell intrinsic effects of GITR and 4-1BB during viral infection and cancer immunotherapy.IAPS and ubiquitylation.The contextual role of TNFR family members in CD8(+) T-cell control of viral infections.The diverse role of RIP kinases in necroptosis and inflammation.Beyond TNF: TNF superfamily cytokines as targets for the treatment of rheumatic diseases.Necroptosis: A Novel Cell Death Modality and Its Potential Relevance for Critical Care Medicine.Induction of the alternative NF-κB pathway by lymphotoxin αβ (LTαβ) relies on internalization of LTβ receptor.IAPs and Cell Death.Characterization of ML-IAP protein stability and physiological role in vivo.A protective strategy against hyperinflammatory responses requiring the nontranscriptional actions of GPS2.Small molecules to the rescue: Inhibition of cytokine signaling in immune-mediated diseases.Coordinated ubiquitination and phosphorylation of RIP1 regulates necroptotic cell death.Necroptosis in the periodontal homeostasis: Signals emanating from dying cells.Lysine acetyltransferase PCAF is a key regulator of arteriogenesis.
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Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs.
@en
Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs.
@nl
type
label
Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs.
@en
Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs.
@nl
prefLabel
Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs.
@en
Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs.
@nl
P2860
P356
P1476
Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs.
@en
P2093
P2860
P2888
P356
10.1038/CDD.2009.114
P50
P577
2010-01-01T00:00:00Z
P5875
P6179
1040788878