Affecting gene expression by altering the length and sequence of the 5' leader.
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The scanning model for translation: an updateSuppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational controlFirefly luciferase gene: structure and expression in mammalian cellsEvidence for regulation of reinitiation in translational control of GCN4 mRNA.Negative and translation termination-dependent positive control of FLI-1 protein synthesis by conserved overlapping 5' upstream open reading frames in Fli-1 mRNA.The 3' untranslated region of the human interferon-beta mRNA has an inhibitory effect on translation.Structure of the galactokinase gene of Escherichia coli, the last (?) gene of the gal operonTwo delta-crystallin polypeptides are derived from a cloned delta 1-crystallin cDNA.Alterations of the three short open reading frames in the Rous sarcoma virus leader RNA modulate viral replication and gene expressionRequirements for intercistronic distance and level of eukaryotic initiation factor 2 activity in reinitiation on GCN4 mRNA vary with the downstream cistron.Effect of mutations and deletions in a bicistronic mRNA on the synthesis of influenza B virus NB and NA glycoproteins.mRNA structures influencing translation in the yeast Saccharomyces cerevisiae.Leader length and secondary structure modulate mRNA function under conditions of stressGenetic selection for mutations that reduce or abolish ribosomal recognition of the HIS4 translational initiator regionMutational analysis of the HIS4 translational initiator region in Saccharomyces cerevisiae.Expression of dicistronic transcriptional units in transgenic tobacco.Leader-encoded open reading frames modulate both the absolute and relative rates of synthesis of the virion proteins of simian virus 40Effects of alterations in the leader sequence of Rous sarcoma virus RNA on initiation of translation.Use of the Escherichia coli gene for asparagine synthetase as a selective marker in a shuttle vector capable of dominant transfection and amplification in animal cells.The positive regulatory function of the 5'-proximal open reading frames in GCN4 mRNA can be mimicked by heterologous, short coding sequences.The first and fourth upstream open reading frames in GCN4 mRNA have similar initiation efficiencies but respond differently in translational control to change in length and sequence.Mechanisms of synthesis of virion proteins from the functionally bigenic late mRNAs of simian virus 40.Effect of upstream reading frames on translation efficiency in simian virus 40 recombinants.Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae.Expression of cloned monkey metallothionein in Escherichia coli.Thymidylate synthase gene of herpesvirus ateles.Deletions in the SV40 late polyadenylation region downstream of the AATAAA mediate similar effects on expression in various mammalian cell lines.Alpha-thalassemia due to the deletion of nucleotides -2 and -3 preceding the AUG initiation codon affects translation efficiency both in vitro and in vivo.Role of the avian retrovirus mRNA leader in expression: evidence for novel translational control.Conserved sequence elements in the 5' region of the Ultrabithorax transcription unit.Both the 5' untranslated region and the sequences surrounding the start site contribute to efficient initiation of translation in vitro.Translation of the mRNA of the maize transcriptional activator Opaque-2 is inhibited by upstream open reading frames present in the leader sequence.mRNA sequences influencing translation and the selection of AUG initiator codons in the yeast Saccharomyces cerevisiae.Effects of long 5' leader sequences on initiation by eukaryotic ribosomes in vitro.Exploring the Role of AUG Triplets in Human Cap-Independent Translation Enhancing Elements
P2860
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P2860
Affecting gene expression by altering the length and sequence of the 5' leader.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1984
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Affecting gene expression by altering the length and sequence of the 5' leader.
@en
Affecting gene expression by altering the length and sequence of the 5' leader.
@nl
type
label
Affecting gene expression by altering the length and sequence of the 5' leader.
@en
Affecting gene expression by altering the length and sequence of the 5' leader.
@nl
prefLabel
Affecting gene expression by altering the length and sequence of the 5' leader.
@en
Affecting gene expression by altering the length and sequence of the 5' leader.
@nl
P2093
P2860
P356
P1476
Affecting gene expression by altering the length and sequence of the 5' leader.
@en
P2093
Johansen H
Rosenberg M
Schümperli D
P2860
P304
P356
10.1073/PNAS.81.24.7698
P407
P577
1984-12-01T00:00:00Z