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BID binds to replication protein A and stimulates ATR function following replicative stressPhysiology of the read-write genomeSld2 binds to origin single-stranded DNA and stimulates DNA annealing.Mcm2 phosphorylation and the response to replicative stressA role for H2B ubiquitylation in DNA replicationLinking DNA replication checkpoint to MBF cell-cycle transcription reveals a distinct class of G1/S genes.Disruption of SUMO-targeted ubiquitin ligases Slx5-Slx8/RNF4 alters RecQ-like helicase Sgs1/BLM localization in yeast and human cells.Bioluminescence imaging of DNA synthetic phase of cell cycle in living animalsAssembly of Slx4 signaling complexes behind DNA replication forksThe Arabidopsis thaliana checkpoint kinase WEE1 protects against premature vascular differentiation during replication stress.MYC and the control of DNA replication.The CRL2LRR-1 ubiquitin ligase regulates cell cycle progression during C. elegans development.Continued primer synthesis at stalled replication forks contributes to checkpoint activation.The extent of error-prone replication restart by homologous recombination is controlled by Exo1 and checkpoint proteins.Arabidopsis thaliana MCM2 plays role(s) in mungbean yellow mosaic India virus (MYMIV) DNA replication.Gallotannin imposes S phase arrest in breast cancer cells and suppresses the growth of triple-negative tumors in vivo.Alpha-synuclein functions in the nucleus to protect against hydroxyurea-induced replication stress in yeast.Top2 and Sgs1-Top3 Act Redundantly to Ensure rDNA Replication Termination.Extracellular signal-regulated kinases modulate DNA damage response - a contributing factor to using MEK inhibitors in cancer therapy.Cell cycle control in acute myeloid leukemia.Dbf4: the whole is greater than the sum of its partsABCE1 is essential for S phase progression in human cellsChromosome Duplication in Saccharomyces cerevisiae.'AND' logic gates at work: Crystal structure of Rad53 bound to Dbf4 and Cdc7.Rad53 downregulates mitotic gene transcription by inhibiting the transcriptional activator Ndd1.Eukaryotic DNA damage checkpoint activation in response to double-strand breaks.The DNA damage checkpoint response to replication stress: A Game of Forks.Resolving branched DNA intermediates with structure-specific nucleases during replication in eukaryotes.Therapeutic targeting the cell division cycle 25 (CDC25) phosphatases in human acute myeloid leukemia--the possibility to target several kinases through inhibition of the various CDC25 isoforms.Hsk1 kinase and Cdc45 regulate replication stress-induced checkpoint responses in fission yeast.The N-terminal 45-kDa domain of Dna2 endonuclease/helicase targets the enzyme to secondary structure DNASUMO-targeted ubiquitin ligase RNF4 plays a critical role in preventing chromosome loss.The human oncoprotein MDM2 induces replication stress eliciting early intra-S-phase checkpoint response and inhibition of DNA replication origin firing.RAD001 (everolimus) induces dose-dependent changes to cell cycle regulation and modifies the cell cycle response to vincristine.Coronavirus infection induces DNA replication stress partly through interaction of its nonstructural protein 13 with the p125 subunit of DNA polymerase δ.DNA replication checkpoint signaling depends on a Rad53-Dbf4 N-terminal interaction in Saccharomyces cerevisiae.Regulators of ribonucleotide reductase inhibit Ty1 mobility in saccharomyces cerevisiae.P-body proteins regulate transcriptional rewiring to promote DNA replication stress resistance.Temporal regulation of the Mus81-Mms4 endonuclease ensures cell survival under conditions of DNA damage.Cell cycle-dependent regulation of the nuclease activity of Mus81-Eme1/Mms4.
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description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 19 August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The S-phase checkpoint: targeting the replication fork.
@en
The S-phase checkpoint: targeting the replication fork.
@nl
type
label
The S-phase checkpoint: targeting the replication fork.
@en
The S-phase checkpoint: targeting the replication fork.
@nl
prefLabel
The S-phase checkpoint: targeting the replication fork.
@en
The S-phase checkpoint: targeting the replication fork.
@nl
P2860
P356
P1433
P1476
The S-phase checkpoint: targeting the replication fork.
@en
P2093
José Antonio Tercero
Mónica Segurado
P2860
P304
P356
10.1042/BC20090053
P577
2009-08-19T00:00:00Z