Analysis of the hippocampal proteome in ME7 prion disease reveals a predominant astrocytic signature and highlights the brain-restricted production of clusterin in chronic neurodegeneration.

Analysis of the hippocampal proteome in ME7 prion disease reveals a predominant astrocytic signature and highlights the brain-restricted production of clusterin in chronic neurodegeneration.

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http://www.wikidata.org/entity/Q37583628
Age and Environment Influences on Mouse Prion Disease Progression: Behavioral Changes and Morphometry and Stereology of Hippocampal Astrocytes.Subtype and regional-specific neuroinflammation in sporadic creutzfeldt-jakob disease.Proteomics analysis of amyloid and nonamyloid prion disease phenotypes reveals both common and divergent mechanisms of neuropathogenesisUpregulation of glycolytic enzymes, mitochondrial dysfunction and increased cytotoxicity in glial cells treated with Alzheimer's disease plasma.Antioxidant peroxiredoxin 6 protein rescues toxicity due to oxidative stress and cellular hypoxia in vitro, and attenuates prion-related pathology in vivoDNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative diseaseProteomics applications in prion biology and structure.Applying the tools of chemistry (mass spectrometry and covalent modification by small molecule reagents) to the detection of prions and the study of their structure.Human stem cell-derived astrocytes replicate human prions in a PRNP genotype-dependent manner.Proteomic Screen of Brain Glycoproteome Reveals Prion Specific Marker of Pathogenesis.
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Analysis of the hippocampal proteome in ME7 prion disease reveals a predominant astrocytic signature and highlights the brain-restricted production of clusterin in chronic neurodegeneration.

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http://www.wikidata.org/entity/Q37583628
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 23 December 2013
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Analysis of the hippocampal pr ...... in chronic neurodegeneration.
@en
Analysis of the hippocampal pr ...... in chronic neurodegeneration.
@nl
type
label
Analysis of the hippocampal pr ...... in chronic neurodegeneration.
@en
Analysis of the hippocampal pr ...... in chronic neurodegeneration.
@nl
prefLabel
Analysis of the hippocampal pr ...... in chronic neurodegeneration.
@en
Analysis of the hippocampal pr ...... in chronic neurodegeneration.
@nl
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P1476
P2093
P2860
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P433
P478
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P5875
P698
P921
P932
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P1433
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Analysis of the hippocampal pr ...... in chronic neurodegeneration.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932