Recent advances in the discovery of haem-targeting drugs for malaria and schistosomiasis.
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The redox biology of schistosome parasites and applications for drug developmentMalarial hemozoin: from target to toolInsights into Integrated Lead Generation and Target Identification in Malaria and Tuberculosis Drug Discovery.Ruthenium(II) arene complexes with chelating chloroquine analogue ligands: synthesis, characterization and in vitro antimalarial activity.A chemotype that inhibits three unrelated pathogenic targets: the botulinum neurotoxin serotype A light chain, P. falciparum malaria, and the Ebola filovirus.Mechanisms of hematin crystallization and inhibition by the antimalarial drug chloroquine.In vitro and in vivo activity of 3-alkoxy-1,2-dioxolanes against Schistosoma mansoni.A physico-biochemical study on potential redox-cyclers as antimalarial and anti-schistosomal drugs.Novel carbazole aminoalcohols as inhibitors of β-hematin formation: Antiplasmodial and antischistosomal activities.Growth of Large Hematin Crystals in Biomimetic Solutions.Stability-indicating HPLC-DAD/UV-ESI/MS impurity profiling of the anti-malarial drug lumefantrine.In Silico Mining for Antimalarial Structure-Activity Knowledge and Discovery of Novel Antimalarial Curcuminoids.Antimalarial efficacy of Pongamia pinnata (L) Pierre against Plasmodium falciparum (3D7 strain) and Plasmodium berghei (ANKA).Pentamethylcyclopentadienyl-rhodium and iridium complexes containing (N^N and N^O) bound chloroquine analogue ligands: synthesis, characterization and antimalarial properties.Interactions between artemisinins and other antimalarial drugs in relation to the cofactor model--a unifying proposal for drug action.Hematin crystallization from aqueous and organic solvents.Antimalarials inhibit hematin crystallization by unique drug-surface site interactions.A novel blood-feeding detoxification pathway in Nippostrongylus brasiliensis L3 reveals a potential checkpoint for arresting hookworm development.
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Recent advances in the discovery of haem-targeting drugs for malaria and schistosomiasis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 04 August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Recent advances in the discovery of haem-targeting drugs for malaria and schistosomiasis.
@en
Recent advances in the discovery of haem-targeting drugs for malaria and schistosomiasis.
@nl
type
label
Recent advances in the discovery of haem-targeting drugs for malaria and schistosomiasis.
@en
Recent advances in the discovery of haem-targeting drugs for malaria and schistosomiasis.
@nl
prefLabel
Recent advances in the discovery of haem-targeting drugs for malaria and schistosomiasis.
@en
Recent advances in the discovery of haem-targeting drugs for malaria and schistosomiasis.
@nl
P2860
P1433
P1476
Recent advances in the discovery of haem-targeting drugs for malaria and schistosomiasis
@en
P2093
Katherine A de Villiers
Timothy J Egan
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P304
P356
10.3390/MOLECULES14082868
P407
P577
2009-08-04T00:00:00Z