Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells. - Wikidata - awgldk - TriplyDB

Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells.

Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells.

http://www.wikidata.org/entity/Q37591111

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Origins, genetic landscape, and emerging therapies of small cell lung cancer Genetically engineered mouse models in oncology research and cancer medicine Imaging tumor metabolism using positron emission tomography Genetic requirement for Mycl and efficacy of RNA Pol I inhibition in mouse models of small cell lung cancer Improved pregnancy and birth rates with routine application of nonsurgical embryo transfer.In vivo models in breast cancer research: progress, challenges and future directions.Dynamic variations in epithelial-to-mesenchymal transition (EMT), ATM, and SLFN11 govern response to PARP inhibitors and cisplatin in small cell lung cancer.Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor INFRAFRONTIER--providing mutant mouse resources as research tools for the international scientific community.Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer.The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung.Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland.Transcription Factor NFIB Is a Driver of Small Cell Lung Cancer Progression in Mice and Marks Metastatic Disease in Patients.Genetic Dissection of Cancer Development, Therapy Response, and Resistance in Mouse Models of Breast Cancer.MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition.NFIB overexpression cooperates with Rb/p53 deletion to promote small cell lung cancer Family matters: How MYC family oncogenes impact small cell lung cancer.Complexity galore: 3D cultures, biomechanics and systems medicine at the eighth ENBDC workshop "Methods in Mammary Gland Development and Cancer".Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer.Transcriptional deregulation underlying the pathogenesis of small cell lung cancer.

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Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells.

http://www.wikidata.org/entity/Q37591111

description

article científic

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article scientifique

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artigo científico

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bilimsel makale

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scientific article published on 08 January 2014

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vedecký článok

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Rapid target gene validation i ...... -derived embryonic stem cells.

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Rapid target gene validation i ...... -derived embryonic stem cells.

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Rapid target gene validation i ...... -derived embryonic stem cells.

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Rapid target gene validation i ...... -derived embryonic stem cells.

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Rapid target gene validation i ...... -derived embryonic stem cells.

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EMBO Molecular Medicine

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Rapid target gene validation i ...... -derived embryonic stem cells.

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Anton Berns

http://www.w3.org/2001/XMLSchema#string

Colin Pritchard

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Hilda de Vries

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Ivo J Huijbers

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Ji-Ying Song

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Jitendra Badhai

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Jos Jonkers

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Kate Sutherland

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Min-Chul Kwon

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Miranda Cozijnsen

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Multiplex genome engineering using CRISPR/Cas systems

Genome editing with engineered zinc finger nucleases

A TALE nuclease architecture for efficient genome editing

Reversible suppression of an essential gene in adult mice using transgenic RNA interference

The ground state of embryonic stem cell self-renewal

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture

Generating embryonic stem cells from the inbred mouse strain DBA/2J, a model of glaucoma and other complex diseases

Production of chimeras by aggregation of embryonic stem cells with diploid or tetraploid mouse embryos

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212-225

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scholarly article

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10.1002/EMMM.201303297

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2

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6

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2014-01-08T00:00:00Z

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259629966

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24401838

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3927956

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