Transcription factor AP2 and its role in epidermal-specific gene expression.
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A family of AP-2 proteins down-regulate manganese superoxide dismutase expressionAn alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2The transglutaminase 1 enzyme is variably acylated by myristate and palmitate during differentiation in epidermal keratinocytesRB and c-Myc activate expression of the E-cadherin gene in epithelial cells through interaction with transcription factor AP-2.Characterization of the regulatory regions in the human desmoglein genes encoding the pemphigus foliaceous and pemphigus vulgaris antigensTranscriptional activation by Myc is under negative control by the transcription factor AP-2The human 230-kD bullous pemphigoid antigen gene (BPAG1). Exon-intron organization and identification of regulatory tissue specific elements in the promoter regionThe genomic structure of the human AP-2 transcription factorOct-6: a regulator of keratinocyte gene expression in stratified squamous epitheliaProfilaggrin is a major epidermal calcium-binding proteinAP-2 gamma and the homeodomain protein distal-less 3 are required for placental-specific expression of the murine 3 beta-hydroxysteroid dehydrogenase VI gene, Hsd3b6Loricrin expression in cultured human keratinocytes is controlled by a complex interplay between transcription factors of the Sp1, CREB, AP1, and AP2 familiesCloning of the gene for human pemphigus vulgaris antigen (desmoglein 3), a desmosomal cadherin. Characterization of the promoter region and identification of a keratinocyte-specific cis-elementCloning and characterization of a novel mouse AP-2 transcription factor, AP-2delta, with unique DNA binding and transactivation propertiesDisruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant miceFunctional interaction between a RARE and an AP-2 binding site in the regulation of the human HOX A4 gene promoterAurora-A interacts with AP-2α and down regulates its transcription activityLarge scale molecular analysis identifies genes with altered expression in salivary adenoid cystic carcinomaLoss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis.Transcriptional enhancer factor (TEF)-1 and its cell-specific co-activator activate human papillomavirus-16 E6 and E7 oncogene transcription in keratinocytes and cervical carcinoma cells.Defining the regulatory factors required for epidermal gene expression.Comparison of CXC chemokines ENA-78 and interleukin-8 expression in Helicobacter pylori-associated gastritis.Functional characterization of the 5' flanking region of human ubiquitin fusion degradation 1 like gene (UFD1L).Neural crest and ectodermal cells intermix in the nasal placode to give rise to GnRH-1 neurons, sensory neurons, and olfactory ensheathing cellsRegulation of the Dlx3 homeobox gene upon differentiation of mouse keratinocytes.Dissection of a complex enhancer element: maintenance of keratinocyte specificity but loss of differentiation specificity.Sp1 and AP2 regulate but do not constitute TATA-less human TAF(II)55 core promoter activity.Identification and dissection of an enhancer controlling epithelial gene expression in skinThe developmentally regulated transcription factor AP-2 is involved in c-erbB-2 overexpression in human mammary carcinoma.Effect of single nucleotide polymorphism Rs189037 in ATM gene on risk of lung cancer in Chinese: a case-control study.Tissue-specific in vivo protein-DNA interactions at the promoter region of the Xenopus 63 kDa keratin gene during metamorphosisExpression of transcription factor AP-2 in colorectal adenomas and adenocarcinomas; comparison of immunohistochemistry and in situ hybridisation.Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 geneInterferon regulatory factor 6 is necessary, but not sufficient, for keratinocyte differentiation.Hoxb1 functions in both motoneurons and in tissues of the periphery to establish and maintain the proper neuronal circuitryDifferential expression of cytokeratin mRNA and protein in normal prostate, prostatic intraepithelial neoplasia, and invasive carcinoma.Differential expression of cytokeratin after orthotopic implantation of newly established human tongue cancer cell lines of defined metastatic abilityBudesonide epimer R or dexamethasone selectively inhibit platelet-activating factor-induced or interleukin 1beta-induced DNA binding activity of cis-acting transcription factors and cyclooxygenase-2 gene expression in human epidermal keratinocytes.Coordinate changes in gene expression which mark the spinous to granular cell transition in epidermis are regulated by protein kinase C.AP2γ regulates neural and epidermal development downstream of the BMP pathway at early stages of ectodermal patterning.
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Transcription factor AP2 and its role in epidermal-specific gene expression.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Transcription factor AP2 and its role in epidermal-specific gene expression.
@en
Transcription factor AP2 and its role in epidermal-specific gene expression.
@nl
type
label
Transcription factor AP2 and its role in epidermal-specific gene expression.
@en
Transcription factor AP2 and its role in epidermal-specific gene expression.
@nl
prefLabel
Transcription factor AP2 and its role in epidermal-specific gene expression.
@en
Transcription factor AP2 and its role in epidermal-specific gene expression.
@nl
P2093
P2860
P356
P1476
Transcription factor AP2 and its role in epidermal-specific gene expression.
@en
P2093
P2860
P304
P356
10.1073/PNAS.88.18.7948
P407
P577
1991-09-01T00:00:00Z