Poly(ADP-ribose) polymerase inhibition in cancer therapy: are we close to maturity? - Wikidata - awgldk - TriplyDB

Poly(ADP-ribose) polymerase inhibition in cancer therapy: are we close to maturity?

Poly(ADP-ribose) polymerase inhibition in cancer therapy: are we close to maturity?

http://www.wikidata.org/entity/Q37594776

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Trial watch - inhibiting PARP enzymes for anticancer therapy Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors Sam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ation Molecular targeting of glioblastoma: Drug discovery and therapies PARP inhibition delays progression of mitochondrial encephalopathy in mice.Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition.Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics.The role of poly adenosine diphosphate ribose polymerase inhibitors in breast and ovarian cancer: current status and future directions.PARP inhibitors: mechanism of action and their potential role in the prevention and treatment of cancer.PARP inhibitors in cancer therapy: an update.Therapeutic Targeting of Poly(ADP-Ribose) Polymerase-1 (PARP1) in Cancer: Current Developments, Therapeutic Strategies, and Future Opportunities.PARP inhibitors as antitumor agents: a patent update (2013-2015).Effect of p53 activity on the sensitivity of human glioblastoma cells to PARP-1 inhibitor in combination with topoisomerase I inhibitor or radiation.Axin1 expression facilitates cell death induced by aurora kinase inhibition through PARP activation.PARP1 in Carcinomas and PARP1 Inhibitors as Antineoplastic Drugs.

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Poly(ADP-ribose) polymerase inhibition in cancer therapy: are we close to maturity?

http://www.wikidata.org/entity/Q37594776

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on October 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Poly(ADP-ribose) polymerase inhibition in cancer therapy: are we close to maturity?

@en

type

label

Poly(ADP-ribose) polymerase inhibition in cancer therapy: are we close to maturity?

@en

prefLabel

Poly(ADP-ribose) polymerase inhibition in cancer therapy: are we close to maturity?

@en

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Expert Opinion on Therapeutic Patents

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Poly(ADP-ribose) polymerase inhibition in cancer therapy: are we close to maturity?

@en

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Alessandra Scolaro

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Alessia Montagnoli

http://www.w3.org/2001/XMLSchema#string

Barbara Forte

http://www.w3.org/2001/XMLSchema#string

Claudia Perrera

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Helena Posteri

http://www.w3.org/2001/XMLSchema#string

Paolo Orsini

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P2860

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

Zinc binding catalytic domain of human tankyrase 1

High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

The Pfam protein families database

In silico characterization of the family of PARP-like poly(ADP-ribosyl)transferases (pARTs)

Resistance-modifying agents. 9. Synthesis and biological properties of benzimidazole inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase

Inhibitor-induced structural change of the active site of human poly(ADP-ribose) polymerase

Crystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2

Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3

Structure of the catalytic fragment of poly(AD-ribose) polymerase from chicken

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1377-1400

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scholarly article

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10.1517/13543770903215883

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10

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19743897

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