Osteocalcin promotes β-cell proliferation during development and adulthood through Gprc6a.
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The Calcium-Sensing Receptor and Integrins in Cellular Differentiation and MigrationThe alliance of mesenchymal stem cells, bone, and diabetesThe Bone Marrow-Derived Stromal Cells: Commitment and Regulation of AdipogenesisAdult tissue sources for new β cells.CRISPR/Cas9 targeting of GPRC6A suppresses prostate cancer tumorigenesis in a human xenograft modelOsteocyte-Secreted Wnt Signaling Inhibitor Sclerostin Contributes to Beige Adipogenesis in Peripheral Fat Depots.Repurposing cAMP-modulating medications to promote β-cell replication.Osteocalcin attenuates high fat diet-induced impairment of endothelium-dependent relaxation through Akt/eNOS-dependent pathway.Carriers of loss-of-function mutations in EXT display impaired pancreatic beta-cell reserve due to smaller pancreas volumeRecent progress in studies of factors that elicit pancreatic β-cell expansionGGCX and VKORC1 inhibit osteocalcin endocrine functions.Effects of moderate amounts of barley in late pregnancy on growth, glucose metabolism and osteoarticular status of pre-weaning horsesAssociation between osteocalcin and glucose metabolism: a meta-analysis.Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone FormationThe effects of acute hyperinsulinemia on bone metabolism.An overview of the metabolic functions of osteocalcinMurine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin VariantsStructural and Functional Evidence for Testosterone Activation of GPRC6A in Peripheral TissuesNew insights into the biology of osteocalcin.GPRC6a is not required for the effects of a high-protein diet on body weight in miceBone and Muscle Endocrine Functions: Unexpected Paradigms of Inter-organ Communication.Inter-organ communication and regulation of beta cell functionEvidence for Osteocalcin Binding and Activation of GPRC6A in β-CellsSearching for additional endocrine functions of the skeleton: genetic approaches and implications for therapeutics.Osteocalcin is necessary and sufficient to maintain muscle mass in older mice.The association between bone turnover markers and microvascular complications of type 2 diabetes.Insulin and bone: Recent developments.GPRC6A: Jack of all metabolism (or master of none).A four-season molecule: osteocalcin. Updates in its physiological roles.Osteocalcin: an osteoblast-derived polypeptide hormone that modulates whole body energy metabolism.Bone, brain & beyond.Osteocalcin-dependent regulation of glucose metabolism and fertility: Skeletal implications for the development of insulin resistance.Low serum osteocalcin concentration is associated with incident type 2 diabetes mellitus in Japanese women.An overview of osteocalcin progress.Molecular Actions of Glucocorticoids in Cartilage and Bone During Health, Disease, and Steroid Therapy.Orientation and conformation of osteocalcin adsorbed onto calcium phosphate and silica surfaces.Exploring inter-organ crosstalk to uncover mechanisms that regulate β-cell function and mass.Advances in β cell replacement and regeneration strategies for treating diabetesBone-Derived Factors: A New Gateway to Regulate Glycemia.Interorgan Crosstalk Contributing to β-Cell Dysfunction.
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Osteocalcin promotes β-cell proliferation during development and adulthood through Gprc6a.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 05 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Osteocalcin promotes β-cell pr ...... and adulthood through Gprc6a.
@en
Osteocalcin promotes β-cell pr ...... and adulthood through Gprc6a.
@nl
type
label
Osteocalcin promotes β-cell pr ...... and adulthood through Gprc6a.
@en
Osteocalcin promotes β-cell pr ...... and adulthood through Gprc6a.
@nl
prefLabel
Osteocalcin promotes β-cell pr ...... and adulthood through Gprc6a.
@en
Osteocalcin promotes β-cell pr ...... and adulthood through Gprc6a.
@nl
P2093
P2860
P356
P1433
P1476
Osteocalcin promotes β-cell pr ...... and adulthood through Gprc6a.
@en
P2093
Gerard Karsenty
Jianwen Wei
Patricia Ducy
Timothy Hanna
P2860
P304
P356
10.2337/DB13-0887
P407
P577
2013-09-05T00:00:00Z