Aryloxy phosphoramidate triesters: a technology for delivering monophosphorylated nucleosides and sugars into cells.
about
Synthesis of nucleoside phosphate and phosphonate prodrugsProdrugs of phosphonates and phosphates: crossing the membrane barrierThe Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug DesignBrønsted acid catalyzed phosphoramidic acid additions to alkenes: diastereo- and enantioselective halogenative cyclizations for the synthesis of C- and P-chiral phosphoramidatesDesign, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides.Correction of a genetic deficiency in pantothenate kinase 1 using phosphopantothenate replacement therapy.Evolution of an amino acid based prodrug approach: stay tuned.Progress in the development of anti-hepatitis C virus nucleoside and nucleotide prodrugs.Nucleoside analogs and tuberculosis: new weapons against an old enemy.Sorting out cirrhosis: mechanisms of non-response to hepatitis C therapy.Flex-nucleoside analogues - Novel therapeutics against filoviruses.Targeting Cancer Cells with a Bisphosphonate Prodrug.Design, synthesis and antiviral evaluation of 2'-C-methyl branched guanosine pronucleotides: the discovery of IDX184, a potent liver-targeted HCV polymerase inhibitor.Synthesis of novel 2',3'-didehydro-2',3'-dideoxyinosine phosphoramidate prodrugs and evaluation of their anticancer activity.Synthesis of novel nucleoside analogue phosphorothioamidate prodrugs and in vitro anticancer evaluation against RKO human colon carcinoma cells.Treatment of breast and lung cancer cells with a N-7 benzyl guanosine monophosphate tryptamine phosphoramidate pronucleotide (4Ei-1) results in chemosensitization to gemcitabine and induced eIF4E proteasomal degradation.Discovery of PSI-353661, a Novel Purine Nucleotide Prodrug for the Treatment of HCV InfectionBifunctional aryloxyphosphoramidate prodrugs of 2'-C-Me-uridine: synthesis and anti-HCV activity.The ProTides Boom.Design, Synthesis and Biological Evaluation of Novel Phosphorylated Abacavir Derivatives as Antiviral Agents Against Newcastle Disease Virus Infection in Chicken.Synthesis and Antiviral Activity of Novel Phosphorylated Derivatives of Didanosine Against Newcastle Disease Virus in Chicken.The protecting-group free selective 3'-functionalization of nucleosidesEfficient synthesis of nucleoside aryloxy phosphoramidate prodrugs utilizing benzyloxycarbonyl protection.Amino acid esters substituted phosphorylated emtricitabine and didanosine derivatives as antiviral and anticancer agents.The DiPPro approach: synthesis, hydrolysis, and antiviral activity of lipophilic d4T diphosphate prodrugs.Kinetin Riboside and Its ProTides Activate the Parkinson's Disease Associated PTEN-Induced Putative Kinase 1 (PINK1) Independent of Mitochondrial DepolarizationEfficient synthesis of exo-N-carbamoyl nucleosides: application to the synthesis of phosphoramidate prodrugs.Synthesis and anti-herpetic activity of phosphoramidate ProTides.Transgene expression of Drosophila melanogaster nucleoside kinase reverses mitochondrial thymidine kinase 2 deficiency.Synthesis and biological evaluation of purine 2'-fluoro-2'-deoxyriboside ProTides as anti-influenza virus agents.Advanced Prodrug Strategies in Nucleoside and Non-Nucleoside Antiviral Agents: A Review of the Recent Five Years.Applying the prodrug strategy to α-phosphonocarboxylate inhibitors of Rab GGTase--synthesis and stability studies.Symmetrical diamidate prodrugs of nucleotide analogues for drug delivery.Influence of the nucleobase and anchimeric assistance of the carboxyl acid groups in the hydrolysis of amino acid nucleoside phosphoramidates.A novel synthesis of antiviral nucleoside phosphoramidate and thiophosphoramidate prodrugs via nucleoside H-phosphonamidates.Amidate Prodrugs of Cyclic 9-()-[3-Hydroxy-2-(phosphonomethoxy)propyl]adenine with Potent Anti-Herpesvirus ActivityNucleobase and Nucleoside Analogues: Resistance and Re-Sensitisation at the Level of Pharmacokinetics, Pharmacodynamics and MetabolismChemical genetic inhibition of DEAD-box proteins using covalent complementarity
P2860
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P2860
Aryloxy phosphoramidate triesters: a technology for delivering monophosphorylated nucleosides and sugars into cells.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Aryloxy phosphoramidate triest ...... eosides and sugars into cells.
@en
Aryloxy phosphoramidate triest ...... eosides and sugars into cells.
@nl
type
label
Aryloxy phosphoramidate triest ...... eosides and sugars into cells.
@en
Aryloxy phosphoramidate triest ...... eosides and sugars into cells.
@nl
prefLabel
Aryloxy phosphoramidate triest ...... eosides and sugars into cells.
@en
Aryloxy phosphoramidate triest ...... eosides and sugars into cells.
@nl
P2860
P50
P356
P1433
P1476
Aryloxy phosphoramidate triest ...... eosides and sugars into cells.
@en
P2860
P304
P356
10.1002/CMDC.200900289
P577
2009-11-01T00:00:00Z