Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function. - Wikidata - awgldk - TriplyDB

Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function.

Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function.

http://www.wikidata.org/entity/Q37598848

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IRIZIO: a novel gene cooperating with PAX3-FOXO1 in alveolar rhabdomyosarcoma (ARMS)IL-4R drives dedifferentiation, mitogenesis, and metastasis in rhabdomyosarcoma New tricks from an old oncogene: gene fusion and copy number alterations of MYB in human cancer Connective tissue fibroblasts and Tcf4 regulate myogenesis PAX3-FOXO1 fusion gene in rhabdomyosarcoma Rhabdomyosarcoma: Advances in Molecular and Cellular Biology Mechanisms of impaired differentiation in rhabdomyosarcoma Potential for immunotherapy in soft tissue sarcoma Virtual histology of transgenic mouse embryos for high-throughput phenotyping.Cell-cycle dependent expression of a translocation-mediated fusion oncogene mediates checkpoint adaptation in rhabdomyosarcoma The case for primary salivary rhabdomyosarcoma Drosophila and mammalian models uncover a role for the myoblast fusion gene TANC1 in rhabdomyosarcoma Modeling Alveolar Soft Part Sarcomagenesis in the Mouse: A Role for Lactate in the Tumor Microenvironment Lineage of origin in rhabdomyosarcoma informs pharmacological response Evasion mechanisms to Igf1r inhibition in rhabdomyosarcoma Embryonic signaling pathways and rhabdomyosarcoma: contributions to cancer development and opportunities for therapeutic targeting PDGFR-A is a therapeutic target in alveolar rhabdomyosarcoma.Regulatory landscape fusion in rhabdomyosarcoma through interactions between the PAX3 promoter and FOXO1 regulatory elements Methodology for the inference of gene function from phenotype data.Structural and functional studies of FKHR-PAX3, a reciprocal fusion gene of the t(2;13) chromosomal translocation in alveolar rhabdomyosarcoma FOXOs, cancer and regulation of apoptosis PDGFRβ reverses EphB4 signaling in alveolar rhabdomyosarcoma.MiR-214 and N-ras regulatory loop suppresses rhabdomyosarcoma cell growth and xenograft tumorigenesis.Transcriptome analyses based on genetic screens for Pax3 myogenic targets in the mouse embryo.Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model Pediatric Rhabdomyosarcoma.Development and potential applications of CRISPR-Cas9 genome editing technology in sarcoma.Immune competency of a hairless mouse strain for improved preclinical studies in genetically engineered mice Genome-wide identification of PAX3-FKHR binding sites in rhabdomyosarcoma reveals candidate target genes important for development and cancer.A Postnatal Pax7 Progenitor Gives Rise to Pituitary Adenomas.Animal models of soft-tissue sarcoma.Impaired Wnt signaling in embryonal rhabdomyosarcoma cells from p53/c-fos double mutant mice.FOXO1: a potential target for human diseases FOXO1-FGFR1 fusion and amplification in a solid variant of alveolar rhabdomyosarcoma.Rb1 loss modifies but does not initiate alveolar rhabdomyosarcoma Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century.Primary alveolar rhabdomyosarcoma of the bone: two cases and review of the literature Evidence for an unanticipated relationship between undifferentiated pleomorphic sarcoma and embryonal rhabdomyosarcoma Conditional activation of MET in differentiated skeletal muscle induces atrophy.Cyclin-dependent kinase 4 phosphorylates and positively regulates PAX3-FOXO1 in human alveolar rhabdomyosarcoma cells

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Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function.

http://www.wikidata.org/entity/Q37598848

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scientific article published on 15 October 2004

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Alveolar rhabdomyosarcomas in ...... RF and Trp53 loss of function.

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Alveolar rhabdomyosarcomas in ...... RF and Trp53 loss of function.

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Alveolar rhabdomyosarcomas in ...... RF and Trp53 loss of function.

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Genes & Development

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Alveolar rhabdomyosarcomas in ...... ARF and Trp53 loss of function

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Benjamin R Arenkiel

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Cheryl M Coffin

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Mario R Capecchi

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Nabeel El-Bardeesy

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Ronald A DePinho

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P2860

Transcriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHR

The muscle regulatory gene, Myf-6, has a biphasic pattern of expression during early mouse development

PAX7 expression in embryonal rhabdomyosarcoma suggests an origin in muscle satellite cells

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

Generalized lacZ expression with the ROSA26 Cre reporter strain

Myc pathways provoking cell suicide and cancer

PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the children's oncology group

Inducible short-term and stable long-term cell culture systems reveal that the PAX3-FKHR fusion oncoprotein regulates CXCR4, PAX3, and PAX7 expression

Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification

Inactivation of Myf-6 and Myf-5 genes in mice leads to alterations in skeletal muscle development

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2614-2626

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10.1101/GAD.1244004

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15489287

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525542

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