Disease mutations in the prion-like domains of hnRNPA1 and hnRNPA2/B1 introduce potent steric zippers that drive excess RNP granule assembly.
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Prion-like domains as epigenetic regulators, scaffolds for subcellular organization, and drivers of neurodegenerative diseaseInsights into muscle degeneration from heritable inclusion body myopathiesEngineering enhanced protein disaggregases for neurodegenerative diseasePrions, amyloids, and RNA: Pieces of a puzzle.Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.Amyotrophic Lateral Sclerosis Type 20 - In Silico Analysis and Molecular Dynamics Simulation of hnRNPA1Isolated inclusion body myopathy caused by a multisystem proteinopathy-linked hnRNPA1 mutationRoles for RNA-binding proteins in development and disease.Genetic mutations in RNA-binding proteins and their roles in ALS.RNA-binding proteins in neurodegeneration: mechanisms in aggregate.The roles of intrinsic disorder-based liquid-liquid phase transitions in the "Dr. Jekyll-Mr. Hyde" behavior of proteins involved in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.Biology and Pathobiology of TDP-43 and Emergent Therapeutic Strategies.Amyloid assembly and disassemblyPhasing in and out
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Disease mutations in the prion-like domains of hnRNPA1 and hnRNPA2/B1 introduce potent steric zippers that drive excess RNP granule assembly.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 29 May 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Disease mutations in the prion ...... e excess RNP granule assembly.
@en
Disease mutations in the prion ...... e excess RNP granule assembly.
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type
label
Disease mutations in the prion ...... e excess RNP granule assembly.
@en
Disease mutations in the prion ...... e excess RNP granule assembly.
@nl
prefLabel
Disease mutations in the prion ...... e excess RNP granule assembly.
@en
Disease mutations in the prion ...... e excess RNP granule assembly.
@nl
P2860
P356
P1476
Disease mutations in the prion ...... ve excess RNP granule assembly
@en
P2093
J Paul Taylor
P2860
P304
P356
10.4161/RDIS.25200
P577
2013-05-29T00:00:00Z