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The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinomaAflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytesDNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards.The chemistry and biology of aflatoxin B(1): from mutational spectrometry to carcinogenesis.Altered DNA mutation spectrum in aflatoxin b1-treated transgenic mice that express the hepatitis B virus x proteinMutational properties of the primary aflatoxin B1-DNA adduct.Dose dependency of aflatoxin B1 binding on human high molecular weight DNA in the activation of proto-oncogeneSterigmatocystin biosynthesis in Aspergillus nidulans requires a novel type I polyketide synthase.T4 DNA polymerase (3'-5') exonuclease, an enzyme for the detection and quantitation of stable DNA lesions: the ultraviolet light exampleQuantitation of aflatoxin B1 adduction within the ribosomal RNA gene sequences of rat liver DNA.AFB(1) -induced mutagenesis of the gpt gene in AS52 cells.Site-specific carcinogen binding to DNA in polytene chromosomes.Characterization of c-Ki-ras and N-ras oncogenes in aflatoxin B1-induced rat liver tumors.Sequence context effects in DNA replication blocks induced by aflatoxin B1Natural product DNA major groove binders.Carcinogen-nucleic acid interactions: equilibrium binding studies of aflatoxins B1 and B2 with DNA and the oligodeoxynucleotide d(ATGCAT)2.Restricted repair of aflatoxin B1 induced damage in alpha DNA of monkey cells.The role of hepatitis B virus in development of primary hepatocellular carcinoma: Part II.The spectrum of mutations at the p53 locus. Evidence for tissue-specific mutagenesis, selection of mutant alleles, and a "gain of function" phenotype.The p53 tumor suppressor protein reduces point mutation frequency of a shuttle vector modified by the chemical mutagens (+/-)7, 8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene, aflatoxin B1 and meta-chloroperoxybenzoic acid.DNA lability induced by nimustine and ramustine in rat glioma cells.Ser-249 p53 mutations in plasma DNA of patients with hepatocellular carcinoma from The Gambia.S-(2-chloroethyl)glutathione-generated p53 mutation spectra are influenced by differential repair rates more than sites of initial dna damage.Site-specific cleavage of double-strand DNA by hydroperoxide of linoleic acid.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1983
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Sequence specificity in aflatoxin B1--DNA interactions
@en
Sequence specificity in aflatoxin B1--DNA interactions.
@nl
type
label
Sequence specificity in aflatoxin B1--DNA interactions
@en
Sequence specificity in aflatoxin B1--DNA interactions.
@nl
prefLabel
Sequence specificity in aflatoxin B1--DNA interactions
@en
Sequence specificity in aflatoxin B1--DNA interactions.
@nl
P2093
P2860
P356
P1476
Sequence specificity in aflatoxin B1--DNA interactions
@en
P2093
K F Muench
M Z Humayun
P2860
P356
10.1073/PNAS.80.1.6
P407
P577
1983-01-01T00:00:00Z