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Matricellular proteins: a sticky affair with cancersEmerging functions of matricellular proteinsMatrikine and matricellular regulators of EGF receptor signaling on cancer cell migration and invasionSPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement MembraneIntegrated analysis of global mRNA and protein expression data in HEK293 cells overexpressing PRL-1.Anti-SPARC oligopeptide inhibits laser-induced CNV in mice.Roles of Copper-Binding Proteins in Breast Cancer.Significance of stromal-1 and stromal-2 signatures and biologic prognostic model in diffuse large B-cell lymphomaLoss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients.SPARC, FOXP3, CD8 and CD45 correlation with disease recurrence and long-term disease-free survival in colorectal cancer.Regulation of fibulin-2 gene expression by integrin α3β1 contributes to the invasive phenotype of transformed keratinocytesThe epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasionSecreted protein acidic and rich in cysteine (SPARC) suppresses angiogenesis by down-regulating the expression of VEGF and MMP-7 in gastric cancer.SPARC mediates metastatic cooperation between CSC and non-CSC prostate cancer cell subpopulations.Novel role for matricellular proteins in the regulation of islet β cell survival: the effect of SPARC on survival, proliferation, and signaling.A p-Median approach for predicting drug response in tumour cells.Aging-related alterations in the extracellular matrix modulate the microenvironment and influence tumor progression.Nifedipine promotes the proliferation and migration of breast cancer cells.Association between SPARC mRNA expression, prognosis and response to neoadjuvant chemotherapy in early breast cancer: a pooled in-silico analysisDownregulation of SPARC expression inhibits the invasion of human trophoblast cells in vitro.Targeting tumor cell motility to prevent metastasis.Opposite Expression of SPARC between the Liver and Pancreas in Streptozotocin-Induced Diabetic RatsGenetic and Immunohistochemical Expression of Integrins ITGAV, ITGA6, and ITGA3 As Prognostic Factor for Colorectal Cancer: Models for Global and Disease-Free SurvivalA new biologic prognostic model based on immunohistochemistry predicts survival in patients with diffuse large B-cell lymphomaThe secreted protein acidic and rich in cysteine (SPARC) induces endoplasmic reticulum stress leading to autophagy-mediated apoptosis in neuroblastoma.PTEN suppresses SPARC-induced pMAPKAPK2 and inhibits SPARC-induced Ser78 HSP27 phosphorylation in gliomaIntercellular adhesion molecule-1 mediates murine colon adenocarcinoma invasion.Caveolin-1 modulates the ability of Ewing's sarcoma to metastasize.SPARC expression and prognostic value in non-small cell lung cancer.Roles of SPARC in urothelial carcinogenesis, progression and metastasis.SPARC overexpression in primary tumors correlates with disease recurrence and overall survival in patients with triple negative breast cancer.Diverse biological functions of the SPARC family of proteins.Antiangiogenic and anticancer molecules in cartilage.Role of SPARC in bone remodeling and cancer-related bone metastasis.A genome-wide SNP scan reveals two loci associated with the chicken resistance to Marek's disease.Analysis of colorectal cancer glyco-secretome identifies laminin β-1 (LAMB1) as a potential serological biomarker for colorectal cancer.Collagen signaling enhances tumor progression after anti-VEGF therapy in a murine model of pancreatic ductal adenocarcinoma.Defining the human copper proteome and analysis of its expression variation in cancers.Secreted protein acidic and rich in cysteine (SPARC) is upregulated by transforming growth factor (TGF)-β and is required for TGF-β-induced hydrogen peroxide production in fibroblastsSPARC functions as an anti-stress factor by inactivating p53 through Akt-mediated MDM2 phosphorylation to promote melanoma cell survival.
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P2860
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 07 October 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
SPARC: a matricellular regulator of tumorigenesis.
@en
SPARC: a matricellular regulator of tumorigenesis.
@nl
type
label
SPARC: a matricellular regulator of tumorigenesis.
@en
SPARC: a matricellular regulator of tumorigenesis.
@nl
prefLabel
SPARC: a matricellular regulator of tumorigenesis.
@en
SPARC: a matricellular regulator of tumorigenesis.
@nl
P2860
P1476
SPARC: a matricellular regulator of tumorigenesis.
@en
P2093
Rolf A Brekken
Shanna A Arnold
P2860
P2888
P304
P356
10.1007/S12079-009-0072-4
P577
2009-10-07T00:00:00Z