Targeting deregulated AMPK/mTORC1 pathways improves muscle function in myotonic dystrophy type I.
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Expanded CCUG repeat RNA expression in Drosophila heart and muscle trigger Myotonic Dystrophy type 1-like phenotypes and activate autophagocytosis genes.Myotonic dystrophy: approach to therapy.Receptor and post-receptor abnormalities contribute to insulin resistance in myotonic dystrophy type 1 and type 2 skeletal muscle.Chronic 5-Aminoimidazole-4-Carboxamide-1-β-d-Ribofuranoside Treatment Induces Phenotypic Changes in Skeletal Muscle, but Does Not Improve Disease Outcomes in the R6/2 Mouse Model of Huntington's Disease.Deficit in PINK1/PARKIN-mediated mitochondrial autophagy at late stages of dystrophic cardiomyopathy.Detection of expanded RNA repeats using thermostable group II intron reverse transcriptase.miR-23b and miR-218 silencing increase Muscleblind-like expression and alleviate myotonic dystrophy phenotypes in mammalian models.Hypoxia impairs adaptation of skeletal muscle protein turnover- and AMPK signaling during fasting-induced muscle atrophy
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Targeting deregulated AMPK/mTORC1 pathways improves muscle function in myotonic dystrophy type I.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 09 January 2017
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Targeting deregulated AMPK/mTO ...... in myotonic dystrophy type I.
@en
Targeting deregulated AMPK/mTO ...... in myotonic dystrophy type I.
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type
label
Targeting deregulated AMPK/mTO ...... in myotonic dystrophy type I.
@en
Targeting deregulated AMPK/mTO ...... in myotonic dystrophy type I.
@nl
prefLabel
Targeting deregulated AMPK/mTO ...... in myotonic dystrophy type I.
@en
Targeting deregulated AMPK/mTO ...... in myotonic dystrophy type I.
@nl
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Targeting deregulated AMPK/mTO ...... in myotonic dystrophy type I.
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Christopher Eickhorst
Kathrin Chojnowska
Marielle Brockhoff
Markus A Rüegg
Michael Sinnreich
Nathalie Rion
Perrine Castets
Stephan Frank
Tatiana Wiktorowicz
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P304
P356
10.1172/JCI89616
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P577
2017-01-09T00:00:00Z