SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts.
about
Tissue factor, protease activated receptors and pathologic heart remodellingThrombin receptors and their antagonists: an update on the patent literatureTissue factor and heart inflammation.Protease-activated receptor-1 contributes to cardiac remodeling and hypertrophyPlasma fibronectin promotes lung metastasis by contributions to fibrin clots and tumor cell invasionInhibiting protease-activated receptor 4 limits myocardial ischemia/reperfusion injury in rat hearts by unmasking adenosine signaling.Increased expression of matrix metalloproteinase-1 in systemic vessels of preeclamptic women: a critical mediator of vascular dysfunction.Modulation of protease activated receptor 1 influences human metapneumovirus disease severity in a mouse modelProtease-activated receptors and myocardial infarctionTissue factor, blood coagulation, and beyond: an overview.The chemistry and pharmacology of privileged pyrroloquinazolines.Effects of thrombin and thrombin receptor activation on cardiac function after acute myocardial infarctionIntraovarian thrombin and activated protein C signaling system regulates steroidogenesis during the periovulatory period.Kallikrein 6 is a novel molecular trigger of reactive astrogliosis.Thrombin activity associated with neuronal damage during acute focal ischemiaDefining the cellular repertoire of GPCRs identifies a profibrotic role for the most highly expressed receptor, protease-activated receptor 1, in cardiac fibroblasts.Stanniocalcin-1 inhibits thrombin-induced signaling and protects from bleomycin-induced lung injury.Contribution of protease-activated receptor 1 in status epilepticus-induced epileptogenesis.Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention?PAR1 contributes to influenza A virus pathogenicity in micePAR-1 contributes to the innate immune response during viral infection.Potent cardioprotection from ischemia-reperfusion injury by a two-domain fusion protein comprising annexin V and Kunitz protease inhibitorProtease-activated receptor 1 inhibition by SCH79797 attenuates left ventricular remodeling and profibrotic activities of cardiac fibroblasts.Parstatin: a cryptic peptide involved in cardioprotection after ischaemia and reperfusion injury10 Gy total body irradiation increases risk of coronary sclerosis, degeneration of heart structure and function in a rat model.Protease-activated receptor 4 deficiency offers cardioprotection after acute ischemia reperfusion injury.A protease-activated receptor 1 antagonist protects against global cerebral ischemia/reperfusion injury after asphyxial cardiac arrest in rabbits.A Linear Temporal Increase in Thrombin Activity and Loss of Its Receptor in Mouse Brain following Ischemic Stroke.Mechanisms and consequences of inflammatory signaling in the myocardium.Cardiac intercellular communication: are myocytes and fibroblasts fair-weather friends?Activation of protease activated receptor 1 increases the excitability of the dentate granule neurons of hippocampusTargeting PAR1: Now What?Argatroban Attenuates Diabetic Cardiomyopathy in Rats by Reducing Fibrosis, Inflammation, Apoptosis, and Protease-Activated Receptor Expression.Thrombin induces ischemic LTP (iLTP): implications for synaptic plasticity in the acute phase of ischemic stroke.β-adrenergic receptor stimulation transactivates protease-activated receptor 1 via matrix metalloproteinase 13 in cardiac cells.Unexpected anti-hypertrophic responses to low-level stimulation of protease-activated receptors in adult rat cardiomyocytes.PAR-1 antagonist SCH79797 ameliorates apoptosis following surgical brain injury through inhibition of ASK1-JNK in rats.Hypercoagulability causes atrial fibrosis and promotes atrial fibrillation.
P2860
Q26824050-44C423DA-BD24-479D-B04D-7F35494BECB9Q28281696-0239C49D-241B-4BA6-AFD3-79F5423B4D8AQ33710090-40D322EB-2CEF-49C1-84E0-770FBDB7C5FAQ33765289-92EDD9AF-FCFE-4171-AD0B-D0841C7D98D7Q33892041-C18057C3-574B-4D2A-84E0-AF3E4220A21AQ34108989-4D55E640-9FC5-43EB-A155-9DAC9C1F9884Q34760729-18FE9140-F823-4E82-B7B3-79FBDE1647C8Q34981539-0E94579B-8EED-4C61-A3C6-0E2ECE452AA6Q35064542-0B7454B1-2F44-4FD5-A964-A5AACC5E3048Q35222618-F0AA249C-CAB5-4892-B5A0-B7BA604C5332Q35546796-20A392A3-1C16-4B0D-AF53-7C6CC826E556Q35682585-B55FD86F-5AA2-4323-B09A-1A3206A26B8DQ35744034-969399DA-A3F9-4EED-95A7-27E6E1B78299Q35910761-2675D42B-23A6-4650-B6D0-550C13CFEF29Q36058083-696FCF9B-318B-4EC4-83EA-031863901E62Q36329742-6D6269D4-5AA8-4555-B516-D50C46EAFED5Q36350579-4BD1C0E0-54CA-49EF-BBF8-B7D4C9B2E15DQ36380440-A424DF91-5461-4466-8217-BE2FA5FD0380Q36497048-3BDDBDCD-49FF-47C9-8E8B-F3A327EEFB15Q36497143-34AF6593-5E27-4800-93CA-03E285DDD180Q36638187-331A2705-193D-4660-A48F-939DFB3F8DD0Q37117537-ACCF0B2A-6E36-49F1-9D9D-7942338CCE23Q37166899-227D15E3-B2B0-49BC-AAA7-4360A46A91B2Q37240950-D8AF3B5C-9010-46FB-844A-5132C971BB89Q37471698-D3705107-E957-4C20-86E8-DA3EA3C8B8FAQ37674817-4A056090-EB69-4D82-9A58-12B731B9F1E8Q37715328-D45EC059-B87F-4B47-932B-6344F212D76CQ37742837-A56B6012-99DD-437F-9F62-CDC8AFF345D1Q38044254-48B42331-AF37-4AF6-A474-29901D80DB4BQ38046798-45711D94-765B-444A-8075-5DA47808B056Q38365545-E232E748-1384-4D36-BE5D-5D37E5A8C66CQ39338913-CEE17982-ACF1-4754-9C66-94308704BF67Q40127983-7D13E504-3273-4CF1-93EC-BC8CF59D3AB5Q41829829-7819462A-64DA-4ED0-852A-392035BFE437Q42219763-1FE9D095-0FAB-44DC-90D3-E676E322977AQ42463329-E7F56E64-524E-466C-BEC4-3E1680E55D55Q42500420-5C809FB8-6C20-412E-9A9F-102BE3860B03Q53123644-CB6C51A9-0465-4AAC-B889-41042F4BF146
P2860
SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 30 April 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
SCH 79797, a selective PAR1 an ...... erfusion injury in rat hearts.
@en
SCH 79797, a selective PAR1 an ...... erfusion injury in rat hearts.
@nl
type
label
SCH 79797, a selective PAR1 an ...... erfusion injury in rat hearts.
@en
SCH 79797, a selective PAR1 an ...... erfusion injury in rat hearts.
@nl
prefLabel
SCH 79797, a selective PAR1 an ...... erfusion injury in rat hearts.
@en
SCH 79797, a selective PAR1 an ...... erfusion injury in rat hearts.
@nl
P2093
P2860
P1476
SCH 79797, a selective PAR1 an ...... erfusion injury in rat hearts.
@en
P2093
Garrett J Gross
Jennifer L Strande
John E Baker
Xiangping Fu
P2860
P2888
P304
P356
10.1007/S00395-007-0653-4
P577
2007-04-30T00:00:00Z