The PIDDosome activates p53 in response to supernumerary centrosomes.
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Caspase-2: an orphan enzyme out of the shadows.The connections of Wnt pathway components with cell cycle and centrosome: side effects or a hidden logic?Caspase-2 deficiency enhances whole-body carbohydrate utilisation and prevents high-fat diet-induced obesity.Cell cycle arrest through indirect transcriptional repression by p53: I have a DREAM.The resurrection of the PIDDosome - emerging roles in the DNA-damage response and centrosome surveillance.Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.A caspase-2-RFXANK interaction and its implication for MHC class II expression.Checkpoint kinase 1 is essential for normal B cell development and lymphomagenesis.STED nanoscopy of the centrosome linker reveals a CEP68-organized, periodic rootletin network anchored to a C-Nap1 ring at centrioles.Once and only once: mechanisms of centriole duplication and their deregulation in disease.Perturbing mitosis for anti-cancer therapy: is cell death the only answer?The nucleolus: A new home for the PIDDosome.Caspase 2 in mitotic catastrophe: The terminator of aneuploid and tetraploid cells.Tumorigenesis: Extra! Extra! Read all about it!Caspases in metabolic disease and their therapeutic potential.The live cell DNA stain SiR-Hoechst induces DNA damage responses and impairs cell cycle progression.Centrosome amplification arises before neoplasia and increases upon p53 loss in tumorigenesis.p53 accumulation following cytokinesis failure in the absence of caspase-2
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P2860
The PIDDosome activates p53 in response to supernumerary centrosomes.
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on January 2017
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The PIDDosome activates p53 in response to supernumerary centrosomes.
@en
The PIDDosome activates p53 in response to supernumerary centrosomes.
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type
label
The PIDDosome activates p53 in response to supernumerary centrosomes.
@en
The PIDDosome activates p53 in response to supernumerary centrosomes.
@nl
prefLabel
The PIDDosome activates p53 in response to supernumerary centrosomes.
@en
The PIDDosome activates p53 in response to supernumerary centrosomes.
@nl
P2093
P2860
P356
P1433
P1476
The PIDDosome activates p53 in response to supernumerary centrosomes.
@en
P2093
Andreas Villunger
Claudia Soratroi
Egon Demetz
Erich A Nigg
Fabian Schuler
Lisa Eiterer
Manuel D Haschka
Stephan Geley
Valentina Sladky
P2860
P356
10.1101/GAD.289728.116
P577
2017-01-01T00:00:00Z