Oncogenic conversion by regulatory changes in transcription factors.
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A conserved retina-specific gene encodes a basic motif/leucine zipper domainThe PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3E2A basic-helix-loop-helix transcription factors are negatively regulated by serum growth factors and by the Id3 proteinEWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1The RxxRxRxxC motif conserved in all Rel/kappa B proteins is essential for the DNA-binding activity and redox regulation of the v-Rel oncoproteinNovel therapy for myocardial infarction: can HGF/Met be beneficial?Gadd45 proteins as critical signal transducers linking NF-kappaB to MAPK cascadesThymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphomaTherapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hindlimb ischemia models: preclinical study for treatment of peripheral arterial disease.Novel regulatory factors interacting with the promoter of the gene encoding the mRNA cap binding protein (eIF4E) and their function in growth regulation.Expression of Ets-1 proto-oncoprotein in gastrointestinal stromal tumors, leiomyomas and schwannomasFunctional interference between the Spi-1/PU.1 oncoprotein and steroid hormone or vitamin receptors.Integrin alpha 5 beta 1 expression negatively regulates cell growth: reversal by attachment to fibronectinA novel and simple methodology to generate subtracted cDNA libraries.Molecular cloning of cDNA encoding the Xenopus homolog of mammalian RelB.Role of proto-oncogene activation in carcinogenesis.A residue of the ETS domain mutated in the v-ets oncogene is essential for the DNA-binding and transactivating properties of the ETS-1 and ETS-2 proteins.Oncogenic conversion of Ets affects redox regulation in-vivo and in-vitro.Distribution of Xrel in the early Xenopus embryo: a cytoplasmic and nuclear gradientNuclear protein phosphorylation and growth control.A novel target cell for c-fos-induced oncogenesis: development of chondrogenic tumours in embryonic stem cell chimeras.The weak, fine-tuned binding of ubiquitous transcription factors to the Il-2 enhancer contributes to its T cell-restricted activity.Retinoids are important cofactors in T cell activation.Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.An essential E box in the promoter of the gene encoding the mRNA cap-binding protein (eukaryotic initiation factor 4E) is a target for activation by c-myc.Identification of downstream-initiated c-Myc proteins which are dominant-negative inhibitors of transactivation by full-length c-Myc proteins.Transcriptional repression by Msx-1 does not require homeodomain DNA-binding sites.Evolution of the oncogenic potential of v-rel: rel-induced expression of immunoregulatory receptors correlates with tumor development and in vitro transformationcis-acting regulatory regions in the long terminal repeat of simian foamy virus type 1.Screening of phage display immunoglobulin libraries by anti-M13 ELISA and whole phage PCRA dominant negative protein kinase C zeta subspecies blocks NF-kappa B activation.Uniform cell-autonomous tumorigenesis of the choroid plexus by papovavirus large T antigensRelB, a new Rel family transcription activator that can interact with p50-NF-kappa B.Inhibitory effect of myristylation on transrepression by FBR (Gag-Fos) proteinPrognostic value of various molecular and cellular features in oral squamous cell carcinomas: a review.Activation of kappa B-specific proteins by estradiol.Transformation by homeobox genes can be mediated by selective transcriptional repression.Structure-function analysis of the maf oncogene product, a member of the b-Zip protein family.An ATF/CREB binding motif is required for aberrant constitutive expression of the MHC class II DR alpha promoter and activation by SV40 T-antigen.
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Oncogenic conversion by regulatory changes in transcription factors.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Oncogenic conversion by regulatory changes in transcription factors.
@en
Oncogenic conversion by regulatory changes in transcription factors.
@nl
type
label
Oncogenic conversion by regulatory changes in transcription factors.
@en
Oncogenic conversion by regulatory changes in transcription factors.
@nl
prefLabel
Oncogenic conversion by regulatory changes in transcription factors.
@en
Oncogenic conversion by regulatory changes in transcription factors.
@nl
P1433
P1476
Oncogenic conversion by regulatory changes in transcription factors.
@en
P2093
P304
P356
10.1016/0092-8674(91)90640-K
P407
P577
1991-01-01T00:00:00Z