Activation of intestinal CFTR Cl- channel by heat-stable enterotoxin and guanylin via cAMP-dependent protein kinase.
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The genetic advantage hypothesis in cystic fibrosis heterozygotes: a murine studyGlycosylation of the receptor guanylate cyclase C: role in ligand binding and catalytic activityActive intestinal chloride secretion in human carriers of cystic fibrosis mutations: an evaluation of the hypothesis that heterozygotes have subnormal active intestinal chloride secretion.Evaluating candidate agents of selective pressure for cystic fibrosisE. coli heat-stable enterotoxin and guanylyl cyclase C: new functions and unsuspected actionsFrom Escherichia coli heat-stable enterotoxin to mammalian endogenous guanylin hormonesCorrection of chloride transport and mislocalization of CFTR protein by vardenafil in the gastrointestinal tract of cystic fibrosis miceIdentification of resveratrol oligomers as inhibitors of cystic fibrosis transmembrane conductance regulator by high-throughput screening of natural products from chinese medicinal plantsAntidiarrheal efficacy and cellular mechanisms of a Thai herbal remedyDisruption of the guanylyl cyclase-C gene leads to a paradoxical phenotype of viable but heat-stable enterotoxin-resistant miceEnteric bacterial toxins: mechanisms of action and linkage to intestinal secretion.Intestinal Enteroids Model Guanylate Cyclase C-Dependent Secretion Induced by Heat-Stable Enterotoxins.Topological mimicry and epitope duplication in the guanylyl cyclase C receptor.Chloride channel inhibition by a red wine extract and a synthetic small molecule prevents rotaviral secretory diarrhoea in neonatal miceNanomolar-Potency Aminophenyl-1,3,5-triazine Activators of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Chloride Channel for Prosecretory Therapy of Dry Eye Diseases.Designing vaccines to neutralize effective toxin delivery by enterotoxigenic Escherichia coli.Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion.Bronchiolar nonciliated secretory (Clara) cells: source of guanylin in the mammalian lungPhysiology of epithelial chloride and fluid secretionRegulation of cell signaling by the cytoplasmic domains of the heat-stable enterotoxin receptor: identification of autoinhibitory and activating motifs.Contribution of the highly conserved EaeH surface protein to enterotoxigenic Escherichia coli pathogenesis.Novel antigens for enterotoxigenic Escherichia coli vaccinesMutual enhancement of virulence by enterotoxigenic and enteropathogenic Escherichia coliInterleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion.Bacterial enterotoxins are associated with resistance to colon cancer.Diarrhea or colorectal cancer: can bacterial toxins serve as a treatment for colon cancer?Guanylate cyclase C limits systemic dissemination of a murine enteric pathogen.Bioactivity-guided fractionation of an antidiarrheal Chinese herb Rhodiola kirilowii (Regel) Maxim reveals (-)-epicatechin-3-gallate and (-)-epigallocatechin-3-gallate as inhibitors of cystic fibrosis transmembrane conductance regulator.Analysis of CFTR interactome in the macromolecular complexes.A comparison of linaclotide and lubiprostone dosing regimens on ion transport responses in human colonic mucosaTargeted inactivation of the mouse guanylin gene results in altered dynamics of colonic epithelial proliferationRegulation of taurine transport by Escherichia coli heat-stable enterotoxin and guanylin in human intestinal cell linesCalcium- and CaMKII-dependent chloride secretion induced by the microsomal Ca(2+)-ATPase inhibitor 2,5-di-(tert-butyl)-1,4-hydroquinone in cystic fibrosis pancreatic epithelial cells.Evidence for a signaling axis by which intestinal phosphate rapidly modulates renal phosphate reabsorption.Meconium ileus caused by mutations in GUCY2C, encoding the CFTR-activating guanylate cyclase 2CHomeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells.Convective washout reduces the antidiarrheal efficacy of enterocyte surface-targeted antisecretory drugsIdentification and molecular characterization of EatA, an autotransporter protein of enterotoxigenic Escherichia coli.Pharmacology and clinical potential of guanylyl cyclase C agonists in the treatment of ulcerative colitis.
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Activation of intestinal CFTR Cl- channel by heat-stable enterotoxin and guanylin via cAMP-dependent protein kinase.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 1994
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Activation of intestinal CFTR ...... cAMP-dependent protein kinase.
@en
Activation of intestinal CFTR ...... cAMP-dependent protein kinase.
@nl
type
label
Activation of intestinal CFTR ...... cAMP-dependent protein kinase.
@en
Activation of intestinal CFTR ...... cAMP-dependent protein kinase.
@nl
prefLabel
Activation of intestinal CFTR ...... cAMP-dependent protein kinase.
@en
Activation of intestinal CFTR ...... cAMP-dependent protein kinase.
@nl
P2093
P2860
P1433
P1476
Activation of intestinal CFTR ...... cAMP-dependent protein kinase
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P2093
P2860
P304
P356
10.1002/J.1460-2075.1994.TB06355.X
P407
P577
1994-03-01T00:00:00Z