Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.
about
GUCY2C reverse transcriptase PCR to stage pN0 colorectal cancer patientsHepatocyte Growth Factor from a Clinical Perspective: A Pancreatic Cancer ChallengeGuanylyl cyclase C as a biomarker in colorectal cancerFrom Escherichia coli heat-stable enterotoxin to mammalian endogenous guanylin hormonesGUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrityAntiobesity pharmacotherapy: new drugs and emerging targetsBile acids initiate lineage-addicted gastroesophageal tumorigenesis by suppressing the EGF receptor-AKT axis.Sildenafil normalizes bowel transit in preclinical models of constipationLack of guanylate cyclase C results in increased mortality in mice following liver injury.Translating colorectal cancer prevention through the guanylyl cyclase C signaling axis.Loss of guanylyl cyclase C (GCC) signaling leads to dysfunctional intestinal barrierThe uroguanylin system and human disease.The paracrine hormone for the GUCY2C tumor suppressor, guanylin, is universally lost in colorectal cancerProsequence switching: an effective strategy to produce biologically active E. coli heat-stable enterotoxin STh.Guanylate cyclase C limits systemic dissemination of a murine enteric pathogen.Bacterial heat-stable enterotoxins: translation of pathogenic peptides into novel targeted diagnostics and therapeutics.A novel CDX2 isoform regulates alternative splicing.A uroguanylin-GUCY2C endocrine axis regulates feeding in mice.Molecular staging individualizing cancer management.Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis.GUCY2C molecular staging personalizes colorectal cancer patient managementGUCY2C: at the intersection of obesity and cancerBardoxolone Methyl Prevents High-Fat Diet-Induced Colon Inflammation in Mice.Pharmacology and clinical potential of guanylyl cyclase C agonists in the treatment of ulcerative colitis.Enterotoxin preconditioning restores calcium-sensing receptor-mediated cytostasis in colon cancer cellsExpression of guanylate cyclase-C, guanylin, and uroguanylin is downregulated proportionally to the ulcerative colitis disease activity index.Guanylyl cyclase structure, function and regulation.Regulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases.GUCY2C ligand replacement to prevent colorectal cancer.Guanylyl cyclase C prevents colon cancer metastasis by regulating tumor epithelial cell matrix metalloproteinase-9Guanylin and uroguanylin are produced by mouse intestinal epithelial cells of columnar and secretory lineage.Intestinal GUCY2C prevents TGF-β secretion coordinating desmoplasia and hyperproliferation in colorectal cancer.Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target.Type 2 cGMP-dependent protein kinase regulates homeostasis by blocking c-Jun N-terminal kinase in the colon epithelium.GCC signaling in colorectal cancer: Is colorectal cancer a paracrine deficiency syndrome?Can colorectal cancer be prevented or treated by oral hormone replacement therapy?The role of cyclic nucleotide signaling pathways in cancer: targets for prevention and treatmentCorruption of homeostatic mechanisms in the guanylyl cyclase C signaling pathway underlying colorectal tumorigenesisRadiometallated peptides targeting guanylate cyclase C and the urokinase-type plasminogen activator receptor.cGMP-dependent protein kinases as potential targets for colon cancer prevention and treatment.
P2860
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P2860
Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Homeostatic control of the cry ...... ting compartment in intestine.
@ast
Homeostatic control of the cry ...... ting compartment in intestine.
@en
type
label
Homeostatic control of the cry ...... ting compartment in intestine.
@ast
Homeostatic control of the cry ...... ting compartment in intestine.
@en
prefLabel
Homeostatic control of the cry ...... ting compartment in intestine.
@ast
Homeostatic control of the cry ...... ting compartment in intestine.
@en
P2093
P2860
P1476
Homeostatic control of the cry ...... ating compartment in intestine
@en
P2093
Giovanni M Pitari
Inna Chervoneva
Jieru E Lin
Stephanie Schulz
P2860
P304
P356
10.2353/AJPATH.2007.070198
P407
P577
2007-11-01T00:00:00Z