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Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variantsGenetic studies of body mass index yield new insights for obesity biologyTM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet contentHuman beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor functionAbdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetesThe influence of 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene promoter on the incidence, growth and operative risk of abdominal aortic aneurysmRaised interleukin-10 is an indicator of poor outcome and enhanced systemic inflammation in patients with acute coronary syndromeADAMTS-4 and -8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaquesGenetic and structural evaluation of fatty acid transport protein-4 in relation to markers of the insulin resistance syndromeGenetic approach to the role of cysteine proteases in the expansion of abdominal aortic aneurysmsExpression of fatty-acid-handling proteins in human adipose tissue in relation to obesity and insulin resistanceEndometrial TIMP-4 mRNA is high at midcycle and in hyperplasia, but down-regulated in malignant tumours. Coordinated expression with MMP-26Matrix metalloproteinase-26 (matrilysin-2) expression is high in endometrial hyperplasia and decreases with loss of histological differentiation in endometrial cancerProgression of coronary atherosclerosis is associated with a common genetic variant of the human stromelysin-1 promoter which results in reduced gene expressionGene expression in atherosclerotic lesion of ApoE deficient miceEffects of fibrate compounds on expression of plasminogen activator inhibitor-1 by cultured endothelial cellsIn silico detection of sequence variations modifying transcriptional regulationInduction of neutrophil gelatinase-associated lipocalin in vascular injury via activation of nuclear factor-kappaBIn vivo stimulation of vascular plasminogen activator inhibitor-1 production by very low-density lipoprotein involves transcription factor binding to a VLDL-responsive elementMHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarctionAssociation between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant dataGenome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular diseaseA variant in LDLR is associated with abdominal aortic aneurysmGenome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysmGenome-wide association study for circulating levels of PAI-1 provides novel insights into its regulationReal-time imaging required for optimal echocardiographic assessment of aortic valve calcification.T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) micemiR-24 limits aortic vascular inflammation and murine abdominal aneurysm development.Network-based analysis of genome wide association data provides novel candidate genes for lipid and lipoprotein traits.AllelicImbalance: an R/bioconductor package for detecting, managing, and visualizing allele expression imbalance data from RNA sequencingThe Q705K polymorphism in NLRP3 is a gain-of-function alteration leading to excessive interleukin-1β and IL-18 production.Alternative promoter usage of the membrane glycoprotein CD36Expression profiling of macrophages from subjects with atherosclerosis to identify novel susceptibility genes.Functional Analysis of the Coronary Heart Disease Risk Locus on Chromosome 21q22.Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.Intima-media thickness of the descending aorta in patients with bicuspid aortic valve.Protein-altering and regulatory genetic variants near GATA4 implicated in bicuspid aortic valve.Candidate Gene Resequencing in a Large Bicuspid Aortic Valve-Associated Thoracic Aortic Aneurysm Cohort: SMAD6 as an Important Contributor.
P50
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P50
description
Zweeds onderzoeker
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Per Eriksson
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Per Eriksson
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Per Eriksson
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P106
P21
P27
P31
P496
0000-0002-5635-2692