Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene.
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Gene expression profiling and chromatin immunoprecipitation identify DBN1, SETMAR and HIG2 as direct targets of SOX11 in mantle cell lymphomaConstitutive activation of the Wnt canonical pathway in mantle cell lymphomaCyclin D- and E-dependent kinases and the p57(KIP2) inhibitor: cooperative interactions in vivoRole of the F-box protein Skp2 in lymphomagenesisInduction of cyclin D1 by simian virus 40 small tumor antigenInsertional mutagenesis reveals progression genes and checkpoints in MYC/Runx2 lymphomasCyclin D1 and mammary carcinoma: new insights from transgenic mouse modelsPhosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformationCyclins and cyclin-dependent kinases: a biochemical viewDisruption of cyclin D1 nuclear export and proteolysis accelerates mammary carcinogenesisAntiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphomaMouse models of cancer as biological filters for complex genomic data.Expression of constitutively nuclear cyclin D1 in murine lymphocytes induces B-cell lymphoma.The murine gammaherpesvirus 68 v-cyclin gene is an oncogene that promotes cell cycle progression in primary lymphocytes.The cancer/testis antigen CAGE with oncogenic potential stimulates cell proliferation by up-regulating cyclins D1 and E in an AP-1- and E2F-dependent manner.Signaling by ABL oncogenes through cyclin D1.Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway.Cyclin K and cyclin D1b are oncogenic in myeloma cells.Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the beta-catenin pathway.Deregulated expression of the polycomb-group protein SUZ12 target genes characterizes mantle cell lymphoma.Plasmacytomagenesis in Eμ-v-abl transgenic mice is accelerated when apoptosis is restrained.Leptin signaling maintains B-cell homeostasis via induction of Bcl-2 and Cyclin D1Rescue of defective mitogenic signaling by D-type cyclins.Responses in mantle cell lymphoma cells to SNS-032 depend on the biological context of each cell line.A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors.Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma.The hematopoietic transcription factor AML1 (RUNX1) is negatively regulated by the cell cycle protein cyclin D3.Inhibition of tumor growth and metastasis by non-small cell lung cancer cells transfected with cyclin D1-targeted siRNAProspective isolation of clonogenic mantle cell lymphoma-initiating cells.NF-kappaB1 can inhibit v-Abl-induced lymphoid transformation by functioning as a negative regulator of cyclin D1 expression.ATM-dependent spontaneous regression of early Eμ-myc-induced murine B-cell leukemia depends on natural killer and T cellsLoss of T cell-mediated antitumor immunity after construct-specific downregulation of retrovirally encoded T-cell receptor expression in vivo.A mouse model of human oral-esophageal cancer.Expression and effects of inhibition of type I insulin-like growth factor receptor tyrosine kinase in mantle cell lymphoma.Mantle cell lymphoma is characterized by inactivation of the ATM gene.Insertional mutagenesis and deep profiling reveals gene hierarchies and a Myc/p53-dependent bottleneck in lymphomagenesis.Paradoxical expression of INK4c in proliferative multiple myeloma tumors: bi-allelic deletion vs increased expression.A cyclin-D1 interaction with BAX underlies its oncogenic role and potential as a therapeutic target in mantle cell lymphoma.Mxi1 and mxi1-0 antagonize N-myc function and independently mediate apoptosis in neuroblastomaCyclin D1 governs adhesion and motility of macrophages.
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Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1994
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Cyclin D1 transgene impedes ly ...... homagenesis with the myc gene.
@en
Cyclin D1 transgene impedes ly ...... homagenesis with the myc gene.
@nl
type
label
Cyclin D1 transgene impedes ly ...... homagenesis with the myc gene.
@en
Cyclin D1 transgene impedes ly ...... homagenesis with the myc gene.
@nl
prefLabel
Cyclin D1 transgene impedes ly ...... homagenesis with the myc gene.
@en
Cyclin D1 transgene impedes ly ...... homagenesis with the myc gene.
@nl
P2093
P2860
P1433
P1476
Cyclin D1 transgene impedes ly ...... homagenesis with the myc gene.
@en
P2093
A W Harris
B J Warner
G J Lindeman
S E Bodrug
P2860
P304
P407
P577
1994-05-01T00:00:00Z