27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.
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Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancerCurrent trends in oxysterol researchOverlapping nongenomic and genomic actions of thyroid hormone and steroidsDifferential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasionMarketed Drugs Can Inhibit Cytochrome P450 27A1, a Potential New Target for Breast Cancer Adjuvant TherapyIdentification of CETP as a molecular target for estrogen positive breast cancer cell death by cholesterol depleting agentsMutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers.Obesity and cancer pathogenesis.PI3K and ERK signaling pathways are involved in differentiation of monocytic cells induced by 27-hydroxycholesterol.Diet-induced obesity links to ER positive breast cancer progression via LPA/PKD-1-CD36 signaling-mediated microvascular remodeling.The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells.The cholesterol metabolite 27-hydroxycholesterol promotes atherosclerosis via proinflammatory processes mediated by estrogen receptor alpha.How many etiological subtypes of breast cancer: two, three, four, or more?Obesity, cholesterol metabolism, and breast cancer pathogenesisFrom empirical to mechanism-based discovery of clinically useful Selective Estrogen Receptor Modulators (SERMs).Cholesterol and breast cancer pathophysiology.The interaction between metabolism, cancer and cardiovascular disease, connected by 27-hydroxycholesterol.The estrogen receptor as a mediator of the pathological actions of cholesterol in breast cancer.Progesterone action in breast, uterine, and ovarian cancers.Metabolic Signatures of Human Breast Cancer.Intratumor cholesteryl ester accumulation is associated with human breast cancer proliferation and aggressive potential: a molecular and clinicopathological study.Obesity and male breast cancer: provocative parallels?Long-Term Follow-Up of the E1199 Phase III Trial Evaluating the Role of Taxane and Schedule in Operable Breast Cancer.Impact of cholesterol on disease progressionThe oxysterol and cholestenoic acid profile of mouse cerebrospinal fluid.Cholesterolomics: An updateOrigin of an ancient hormone/receptor couple revealed by resurrection of an ancestral estrogenThe pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancerLiver X receptor ligand cytotoxicity in colon cancer cells and not in normal colon epithelial cells depends on LXRβ subcellular localization.The molecular, cellular and clinical consequences of targeting the estrogen receptor following estrogen deprivation therapy.Lipoprotein subfractions by nuclear magnetic resonance are associated with tumor characteristics in breast cancer.The cholesterol metabolite 27-hydroxycholesterol regulates p53 activity and increases cell proliferation via MDM2 in breast cancer cells.Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas.The Hippo pathway, p53 and cholesterolHMG-CoAR expression in male breast cancer: relationship with hormone receptors, Hippo transducers and survival outcomes.ApoA-I mimetic administration, but not increased apoA-I-containing HDL, inhibits tumour growth in a mouse model of inherited breast cancer.Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.High expression of cholesterol biosynthesis genes is associated with resistance to statin treatment and inferior survival in breast cancer.Evaluation of novel derivatisation reagents for the analysis of oxysterols.A High-Cholesterol Diet Increases 27-Hydroxycholesterol and Modifies Estrogen Receptor Expression and Neurodegeneration in Rabbit Hippocampus.
P2860
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P2860
27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.
@en
27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.
@nl
type
label
27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.
@en
27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.
@nl
prefLabel
27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.
@en
27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.
@nl
P2093
P2860
P1433
P1476
27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth
@en
P2093
Bonne Thompson
Chieko Mineo
David M Euhus
Ivan S Yuhanna
Jeffrey G McDonald
Luc Girard
Michihisa Umetani
Philip W Shaul
P2860
P304
P356
10.1016/J.CELREP.2013.10.006
P577
2013-11-07T00:00:00Z