Homing endonucleases: from basics to therapeutic applications.
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Homing endonucleases: DNA scissors on a missionMolecular basis of engineered meganuclease targeting of the endogenous human RAG1 locusTapping natural reservoirs of homing endonucleases for targeted gene modificationNon-specific protein-DNA interactions control I-CreI target binding and cleavageVisualizing phosphodiester-bond hydrolysis by an endonucleaseDevelopment of synthetic selfish elements based on modular nucleases in Drosophila melanogaster.Successful targeting and disruption of an integrated reporter lentivirus using the engineered homing endonuclease Y2 I-AniI.Directed evolution of adeno-associated virus for enhanced gene delivery and gene targeting in human pluripotent stem cells.Circular permutation of a synthetic eukaryotic chromosome with the telomeratorGenetic therapies for cystic fibrosis lung diseaseTALE-PvuII fusion proteins--novel tools for gene targeting.HomeRun Vector Assembly System: a flexible and standardized cloning system for assembly of multi-modular DNA constructs.Homing endonucleases: from genetic anomalies to programmable genomic clippersEngineering a Nickase on the Homing Endonuclease I-DmoI Scaffold.Monomeric site-specific nucleases for genome editing.Crystal Structure of the Homing Endonuclease I-CvuI Provides a New Template for Genome Modification.Vika/vox, a novel efficient and specific Cre/loxP-like site-specific recombination system.Crystallization and preliminary X-ray diffraction analysis of the homing endonuclease I-CvuI from Chlorella vulgaris in complex with its target DNA.Gene conversion in human genetic disease.Transient DNA / RNA-protein interactions.Generation of novel nucleases with extended specificity by rational and combinatorial strategies.Artificial DNA cutters for DNA manipulation and genome engineering.Genetic strategies for the treatment of sickle cell anaemia.Molecular scissors for in situ cellular repair.Restriction endonucleases: natural and directed evolution.Recent advances in targeted genome engineering in mammalian systems.Targeted mutagenesis tools for modelling psychiatric disorders.Technology developments in biological tools for targeted genome surgery.EheA from Exiguobacterium sp. yc3 is a novel thermostable DNase belonging to HNH endonuclease superfamily.Site- and strand-specific nicking of DNA by fusion proteins derived from MutH and I-SceI or TALE repeatsCreating highly specific nucleases by fusion of active restriction endonucleases and catalytically inactive homing endonucleases.rDNA-directed integration by an HIV-1 integrase--I-PpoI fusion proteinGenome sequence of temperate bacteriophage Psymv2 from Antarctic Dry Valley soil isolate Psychrobacter sp. MV2.Insertion of Group II Intron-Based Ribozyme Switches into Homing Endonuclease Genes.[Fight against malaria with genetically modified mosquitoes].Three new active members of the I-OnuI family of homing endonucleases.Bricks and blueprints: methods and standards for DNA assembly.
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Homing endonucleases: from basics to therapeutic applications.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on March 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Homing endonucleases: from basics to therapeutic applications.
@en
Homing endonucleases: from basics to therapeutic applications.
@nl
type
label
Homing endonucleases: from basics to therapeutic applications.
@en
Homing endonucleases: from basics to therapeutic applications.
@nl
prefLabel
Homing endonucleases: from basics to therapeutic applications.
@en
Homing endonucleases: from basics to therapeutic applications.
@nl
P2860
P50
P1476
Homing endonucleases: from basics to therapeutic applications
@en
P2093
Guillermo Montoya
Jesús Prieto
P2860
P2888
P304
P356
10.1007/S00018-009-0188-Y
P577
2010-03-01T00:00:00Z