Human genetics illuminates the paths to metabolic disease.
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Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locusSTK35L1 associates with nuclear actin and regulates cell cycle and migration of endothelial cellsThe arrestin domain-containing 3 protein regulates body mass and energy expenditurePrenatal Exposure to BPA and Offspring Outcomes: The Diabesogenic Behavior of BPADissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing toolsInvolvement of protein tyrosine phosphatases in adipogenesis: new anti-obesity targets?The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiologyA gain-of-function mutation in adenylate cyclase 3 protects mice from diet-induced obesityGenetic & epigenetic approach to human obesityGenetics of type 2 diabetes: pathophysiologic and clinical relevanceThe role of the prokineticin 2 pathway in human reproduction: evidence from the study of human and murine gene mutationsAssessment of infantile mineral imbalances in autism spectrum disorders (ASDs)Integrating human omics data to prioritize candidate genesThe role of genetics in the etiology of schizophreniaA treasure trove of hypothalamic neurocircuitries governing body weight homeostasisIntervention, integration and translation in obesity research: Genetic, developmental and metaorganismal approaches.Circadian intervention of obesity development via resting-stage feeding manipulation or oxytocin treatmentExercise training, genetics and type 2 diabetes-related phenotypes.metabolicMine: an integrated genomics, genetics and proteomics data warehouse for common metabolic disease research.A genome-wide association study confirms previously reported loci for type 2 diabetes in Han ChineseChildhood obesity: a life-long health riskIs there a paradox in obesity?Evaluation of the association between the AC3 genetic polymorphisms and obesity in a Chinese Han population.Quantitative secretome and glycome of primary human adipocytes during insulin resistance.Impact of rs361072 in the phosphoinositide 3-kinase p110beta gene on whole-body glucose metabolism and subunit protein expression in skeletal muscleMelanocortin-3 receptors and metabolic homeostasis.A genomic atlas of mouse hypothalamic development.Synthetic associations are unlikely to account for many common disease genome-wide association signalsInactivation of the Rcan2 gene in mice ameliorates the age- and diet-induced obesity by causing a reduction in food intake.The Missing lnc(RNA) between the pancreatic β-cell and diabetesGenetic control of de novo lipogenesis: role in diet-induced obesityMulti-tissue computational modeling analyzes pathophysiology of type 2 diabetes in MKR mice.Meal parameters and vagal gastrointestinal afferents in mice that experienced early postnatal overnutritionNeurocognitive phenotypes and genetic dissection of disorders of brain and behavior.Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distributionLack of association between body mass index and plasma adiponectin levels in healthy adults.Complete mitochondrial genome sequencing reveals novel haplotypes in a Polynesian population.Y1 and Y5 receptors are both required for the regulation of food intake and energy homeostasis in miceNovel genes upregulated when NOTCH signalling is disrupted during hypothalamic development.Genome-wide analysis of DNA methylation differences in muscle and fat from monozygotic twins discordant for type 2 diabetes.
P2860
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P2860
Human genetics illuminates the paths to metabolic disease.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Human genetics illuminates the paths to metabolic disease.
@en
Human genetics illuminates the paths to metabolic disease.
@nl
type
label
Human genetics illuminates the paths to metabolic disease.
@en
Human genetics illuminates the paths to metabolic disease.
@nl
prefLabel
Human genetics illuminates the paths to metabolic disease.
@en
Human genetics illuminates the paths to metabolic disease.
@nl
P2860
P356
P1433
P1476
Human genetics illuminates the paths to metabolic disease.
@en
P2860
P2888
P304
P356
10.1038/NATURE08532
P407
P577
2009-11-01T00:00:00Z