A protein kinase is present in a complex with adenovirus E1A proteins
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A region in the C-terminus of adenovirus 2/5 E1a protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation, tumorigenesis and metastasisInduction of AP-1 DNA-binding activity and c-fos mRNA by the adenovirus 243R E1A protein and cyclic AMP requires domains necessary for transformation.Human papillomavirus type 16 E7 associates with a histone H1 kinase and with p107 through sequences necessary for transformation.cdc2 cyclin-dependent kinase binds and phosphorylates herpes simplex virus 1 U(L)42 DNA synthesis processivity factorRegulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts.Association of p300 and CBP with simian virus 40 large T antigenThe adenovirus E1A-associated kinase consists of cyclin E-p33cdk2 and cyclin A-p33cdk2.UL34, the target of the herpes simplex virus U(S)3 protein kinase, is a membrane protein which in its unphosphorylated state associates with novel phosphoproteinsAdenovirus E4orf4 protein reduces phosphorylation of c-Fos and E1A proteins while simultaneously reducing the level of AP-1Cyclin-dependent kinases phosphorylate the adenovirus E1A protein, enhancing its ability to bind pRb and disrupt pRb-E2F complexes.Reduced phosphorylation of p50 is responsible for diminished NF-kappaB binding to the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells.E1A 12S and 13S of the transformation-defective adenovirus type 12 strain CS-1 inactivate proteins of the RB family, permitting transactivation of the E2F-dependent promoter.Downregulation of Waf1, C2, C3, and major histocompatibility complex class I loci within an 18-cM region of chromosome 17 in adenovirus-transformed mouse cells.
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A protein kinase is present in a complex with adenovirus E1A proteins
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on December 1991
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A protein kinase is present in a complex with adenovirus E1A proteins
@en
A protein kinase is present in a complex with adenovirus E1A proteins.
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type
label
A protein kinase is present in a complex with adenovirus E1A proteins
@en
A protein kinase is present in a complex with adenovirus E1A proteins.
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prefLabel
A protein kinase is present in a complex with adenovirus E1A proteins
@en
A protein kinase is present in a complex with adenovirus E1A proteins.
@nl
P2860
P356
P1476
A protein kinase is present in a complex with adenovirus E1A proteins
@en
P2093
T Kleinberger
P2860
P304
11143-11147
P356
10.1073/PNAS.88.24.11143
P407
P577
1991-12-01T00:00:00Z