Role of the PACAP-PAC1-DISC1 and PACAP-PAC1-stathmin1 systems in schizophrenia and bipolar disorder: novel treatment mechanisms? - Wikidata - awgldk - TriplyDB

Role of the PACAP-PAC1-DISC1 and PACAP-PAC1-stathmin1 systems in schizophrenia and bipolar disorder: novel treatment mechanisms?

Role of the PACAP-PAC1-DISC1 and PACAP-PAC1-stathmin1 systems in schizophrenia and bipolar disorder: novel treatment mechanisms?

http://www.wikidata.org/entity/Q37643689

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Genetic and metabolic characterization of insomnia Modeling mania in preclinical settings: A comprehensive review.Transcriptomic analysis of genetically defined autism candidate genes reveals common mechanisms of action VIP and PACAP: recent insights into their functions/roles in physiology and disease from molecular and genetic studies.Molecular basis of major psychiatric diseases such as schizophrenia and depression.Neuroleptic Drugs and PACAP Differentially Affect the mRNA Expression of Genes Encoding PAC1/VPAC Type Receptors.

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Role of the PACAP-PAC1-DISC1 and PACAP-PAC1-stathmin1 systems in schizophrenia and bipolar disorder: novel treatment mechanisms?

http://www.wikidata.org/entity/Q37643689

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on December 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Role of the PACAP-PAC1-DISC1 a ...... r: novel treatment mechanisms?

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Role of the PACAP-PAC1-DISC1 a ...... r: novel treatment mechanisms?

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Role of the PACAP-PAC1-DISC1 a ...... r: novel treatment mechanisms?

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Role of the PACAP-PAC1-DISC1 a ...... r: novel treatment mechanisms?

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Role of the PACAP-PAC1-DISC1 a ...... r: novel treatment mechanisms?

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Role of the PACAP-PAC1-DISC1 a ...... r: novel treatment mechanisms?

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Role of the PACAP-PAC1-DISC1 a ...... r: novel treatment mechanisms?

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Kohei Yamada

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Masaya Tohyama

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Shinsuke Matsuzaki

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Taiichi Katayama

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Tsuyoshi Hattori

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P2860

DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation

DISC1-kendrin interaction is involved in centrosomal microtubule network formation

Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling

DISC1 localizes to the centrosome by binding to kendrin

Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth

Mammalian homologue of the Caenorhabditis elegans UNC-76 protein involved in axonal outgrowth is a protein kinase C zeta-interacting protein

A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system

Disruption of two novel genes by a translocation co-segregating with schizophrenia

Yeast two-hybrid screens implicate DISC1 in brain development and function

Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth

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1967-1978

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10.2217/PGS.09.147

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12

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19958095

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P921

bipolar disorder