Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth - Wikidata - awgldk - TriplyDB

Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth

Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth

http://www.wikidata.org/entity/Q24541302

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The cytoskeletal protein Ndel1 regulates dynamin 2 GTPase activity Serine racemase binds to PICK1: potential relevance to schizophrenia Disrupted-in-schizophrenia 1 (DISC1) plays essential roles in mitochondria in collaboration with Mitofilin Nucleocytoplasmic shuttling of dysbindin-1, a schizophrenia-related protein, regulates synapsin I expression Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls Inhibition of NUDEL (nuclear distribution element-like)-oligopeptidase activity by disrupted-in-schizophrenia 1 Functional genomics in postmortem human brain: abnormalities in a DISC1 molecular pathway in schizophrenia DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms Associating schizophrenia, long non-coding RNAs and neurostructural dynamics Neuronal migration abnormalities and its possible implications for schizophrenia DISC1: a key lead in studying cortical development and associated brain disorders An essential role for DYF-11/MIP-T3 in assembling functional intraflagellar transport complexes Regulation of the actin cytoskeleton by the Ndel1-Tara complex is critical for cell migration.Molecular genetic studies of schizophrenia The DISC locus in psychiatric illness A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder DISC1 and DISC2: discovering and dissecting molecular mechanisms underlying psychiatric illness DISC1-binding proteins in neural development, signalling and schizophrenia A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia DISC1: Structure, Function, and Therapeutic Potential for Major Mental Illness Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212 DISC1 regulates cell-cell adhesion, cell-matrix adhesion and neurite outgrowth Dysbindin-1, WAVE2 and Abi-1 form a complex that regulates dendritic spine formation A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development Dixdc1 is a critical regulator of DISC1 and embryonic cortical development Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence Impaired fast-spiking interneuron function in a genetic mouse model of depression.Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits.Gestational methylazoxymethanol acetate administration: a developmental disruption model of schizophrenia.MEG auditory evoked fields suggest altered structural/functional asymmetry in primary but not secondary auditory cortex in bipolar disorder.Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly.What happens in the brain of schizophrenia patients?: an investigation from the viewpoint of neuropathology.Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness A novel DISC1-interacting partner DISC1-Binding Zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth.Dual constraints on synapse formation and regression in schizophrenia: neuregulin, neuroligin, dysbindin, DISC1, MuSK and agrin.Neuropathology of schizophrenia: a mini review.Developmental disruptions in neural connectivity in the pathophysiology of schizophrenia.

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Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth

http://www.wikidata.org/entity/Q24541302

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2003 nî lūn-bûn

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2003 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2003 թվականի հունվարին հրատարակված գիտական հոդված

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2003年の論文

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Disrupted-in-Schizophrenia-1 ( ...... and inhibits neurite outgrowth

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Disrupted-in-Schizophrenia-1 ( ...... and inhibits neurite outgrowth

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Disrupted-in-Schizophrenia-1 ( ...... and inhibits neurite outgrowth

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Disrupted-in-Schizophrenia-1 ( ...... and inhibits neurite outgrowth

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Proceedings of the National Academy of Sciences of the United States of America

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Akira Sawa

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Atsushi Kamiya

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John Kleiderlein

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Kumiko Fujii

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Lyuda Bord

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Mary E Hatten

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Masako Okawa

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Naoto Yamada

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Toshifumi Tomoda

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Yuji Ozeki

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P2860

Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions

Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor acetylhydrolase [corrected]

Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.

Direct association of LIS1, the lissencephaly gene product, with a mammalian homologue of a fungal nuclear distribution protein, rNUDE

Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON

A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system

NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein

Disruption of two novel genes by a translocation co-segregating with schizophrenia

Alpha-synuclein and neurodegenerative diseases

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Solomon Halbert Snyder

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