Predicting drug disposition via application of a Biopharmaceutics Drug Disposition Classification System.
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How drugs get into cells: tested and testable predictions to help discriminate between transporter-mediated uptake and lipoidal bilayer diffusionThe use of ROC analysis for the qualitative prediction of human oral bioavailability from animal data.Relationship between characteristics of medications and drug-induced liver disease phenotype and outcome.A highly sensitive liquid chromatography tandem mass spectrometry method for simultaneous quantification of midazolam, 1'-hydroxymidazolam and 4-hydroxymidazolam in human plasma.Bioequivalence Comparison of Two Formulations of Fixed-Dose Combination Glimepiride/Metformin (2/500 mg)Tablets in Healthy VolunteersBDDCS applied to over 900 drugs.Dedication to professor Leslie Z. Benet: 50 years of scientific excellence and still going strong!Drug Dosing and Pharmacokinetics in Children With Obesity: A Systematic ReviewGaps in Drug Dosing for Obese Children: A Systematic Review of Commonly Prescribed Emergency Care Medications.Physiologically based pharmacokinetic models: integration of in silico approaches with micro cell culture analogues.Novel methods to assess bioequivalence.Interplay of pharmacogenetic variations in ABCB1 transporters and cytochrome P450 enzymes.Current regulatory approaches of bioequivalence testing.The role of BCS (biopharmaceutics classification system) and BDDCS (biopharmaceutics drug disposition classification system) in drug developmentThe influence of bypass procedures and other anatomical changes in the gastrointestinal tract on the oral bioavailability of drugs.In vitro and in vivo approaches to characterize transporter-mediated disposition in drug discovery.Drug delivery: lessons to be learnt from Leishmania studies.Self-nano-emulsifying drug delivery systems: an update of the biopharmaceutical aspects.Reliability of In Vitro and In Vivo Methods for Predicting the Effect of P-Glycoprotein on the Delivery of Antidepressants to the Brain.Binary and ternary cocrystals of sulfa drug acetazolamide with pyridine carboxamides and cyclic amidesMass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axisThe pharmacokinetics of daclatasvir and asunaprevir administered in combination in studies in healthy subjects and patients infected with hepatitis C virus.Elucidating the role of dose in the biopharmaceutics classification of drugs: the concepts of critical dose, effective in vivo solubility, and dose-dependent BCS.Population pharmacokinetic analysis of glimepiride with CYP2C9 genetic polymorphism in healthy Korean subjects.Plasma Pharmacokinetics of Veledimex, a Small-Molecule Activator Ligand for a Proprietary Gene Therapy Promoter System, in Healthy Subjects.Evaluation of DILI Predictive Hypotheses in Early Drug Development.Tacrolimus dose requirements in paediatric renal allograft recipients are characterized by a biphasic course determined by age and bone maturation.Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model II: Verification of the model for passive placental permeability drugs.Safety, Tolerability and Pharmacokinetic and Pharmacodynamic Learnings from a Double-Blind, Randomized, Placebo-Controlled, Sequential Group First-in-Human Study of the TRPV1 Antagonist, JNJ-38893777, in Healthy Men.Influence of verapamil on the pharmacokinetics of oxcarbazepine and of the enantiomers of its 10-hydroxy metabolite in healthy volunteers.In Vitro and In Situ evaluation of pH-dependence of atazanavir intestinal permeability and interactions with acid-reducing agents
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P2860
Predicting drug disposition via application of a Biopharmaceutics Drug Disposition Classification System.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 07 December 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Predicting drug disposition vi ...... osition Classification System.
@en
Predicting drug disposition vi ...... osition Classification System.
@nl
type
label
Predicting drug disposition vi ...... osition Classification System.
@en
Predicting drug disposition vi ...... osition Classification System.
@nl
prefLabel
Predicting drug disposition vi ...... osition Classification System.
@en
Predicting drug disposition vi ...... osition Classification System.
@nl
P2860
P1476
Predicting drug disposition vi ...... osition Classification System.
@en
P2093
Leslie Z Benet
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P304
P356
10.1111/J.1742-7843.2009.00498.X
P577
2009-12-07T00:00:00Z