Targeting the intracellular WT1 oncogene product with a therapeutic human antibody.
about
Wilms tumor 1 mutations in the pathogenesis of acute myeloid leukemiaT cell receptor mimic antibodies for cancer therapyImmunotherapy of Childhood SarcomasSpecificity delivers: therapeutic role of tumor antigen-specific antibodies in pancreatic cancerAdoptive T-cell therapy for LeukemiaTherapeutic bispecific T-cell engager antibody targeting the intracellular oncoprotein WT1.Current issues in malignant pleural mesothelioma evaluation and managementStructure of a TCR-Mimic Antibody with Target Predicts Pharmacogenetics.Strategies to genetically engineer T cells for cancer immunotherapy.A TCR-mimic antibody to WT1 bypasses tyrosine kinase inhibitor resistance in human BCR-ABL+ leukemiasTherapeutic efficacy of an Fc-enhanced TCR-like antibody to the intracellular WT1 oncoprotein.Chimeric antigen receptor T cell therapy in AML: How close are we?Prognostic significance of specific anti-WT1 IgG antibody level in plasma in patients with ovarian carcinomaWilms' tumor 1 (WT1) expression and prognosis in solid cancer patients: a systematic review and meta-analysis.Hypoxia-sensitive epigenetic regulation of an antisense-oriented lncRNA controls WT1 expression in myeloid leukemia cellsFeasibility analysis of p62 (SQSTM1)-encoding DNA vaccine as a novel cancer immunotherapy.Affinity maturation of T-cell receptor-like antibodies for Wilms tumor 1 peptide greatly enhances therapeutic potential.Inducible T-cell receptor expression in precursor T cells for leukemia control.Activity of 8F4, a T-cell receptor-like anti-PR1/HLA-A2 antibody, against primary human AML in vivoApproaching untargetable tumor-associated antigens with antibodies.Oncogenic roles of PRL-3 in FLT3-ITD induced acute myeloid leukaemia.Adoptive T cell transfer for cancer immunotherapy in the era of synthetic biology.CAR T cells for acute myeloid leukemia: the LeY of the land.Targeting Epstein-Barr virus-transformed B lymphoblastoid cells using antibodies with T-cell receptor-like specificitiesAssociation of WT1 IgG antibody against WT1 peptide with prolonged survival in glioblastoma multiforme patients vaccinated with WT1 peptide.CAR therapy for hematological cancers: can success seen in the treatment of B-cell acute lymphoblastic leukemia be applied to other hematological malignancies?Antibody therapy for acute myeloid leukaemia.Adoptive immunotherapy for cancer.Adoptive immunotherapy with genetically modified lymphocytes in allogeneic stem cell transplantation.Canonical and new generation anticancer drugs also target energy metabolism.Going viral: chimeric antigen receptor T-cell therapy for hematological malignancies.Antigen-specific immunotherapy for acute myeloid leukemia: where are we now, and where do we go from here?A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens.An immunogenic WT1-derived peptide that induces T cell response in the context of HLA-A*02:01 and HLA-A*24:02 molecules.Opportunities and challenges for TCR mimic antibodies in cancer therapyEngineered T cells: the promise and challenges of cancer immunotherapy.Retargeting NK-92 for anti-melanoma activity by a TCR-like single-domain antibody.TCR-like antibodies mediate complement and antibody-dependent cellular cytotoxicity against Epstein-Barr virus-transformed B lymphoblastoid cells expressing different HLA-A*02 microvariants.Optimized T-cell receptor-mimic chimeric antigen receptor T cells directed toward the intracellular Wilms Tumor 1 antigen.Mechanisms of leukemia resistance to antibody dependent cellular cytotoxicity.
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Targeting the intracellular WT1 oncogene product with a therapeutic human antibody.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Targeting the intracellular WT1 oncogene product with a therapeutic human antibody.
@en
Targeting the intracellular WT1 oncogene product with a therapeutic human antibody.
@nl
type
label
Targeting the intracellular WT1 oncogene product with a therapeutic human antibody.
@en
Targeting the intracellular WT1 oncogene product with a therapeutic human antibody.
@nl
prefLabel
Targeting the intracellular WT1 oncogene product with a therapeutic human antibody.
@en
Targeting the intracellular WT1 oncogene product with a therapeutic human antibody.
@nl
P2093
P2860
P1476
Targeting the intracellular WT1 oncogene product with a therapeutic human antibody
@en
P2093
David A Scheinberg
Dmitry Pankov
Ekaterina Doubrovina
Emily Casey
Joseph Whitten
Liang Zhou
Michael Curcio
Nicholas Veomett
P2860
P304
P356
10.1126/SCITRANSLMED.3005661
P407
P577
2013-03-01T00:00:00Z