Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancers. - Wikidata - awgldk - TriplyDB

Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancers.

Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancers.

http://www.wikidata.org/entity/Q37660073

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PLCε mediated sustained signaling pathways.Thrombin promotes sustained signaling and inflammatory gene expression through the CDC25 and Ras-associating domains of phospholipase Cϵ Targeting oncogenic PLCE1 by miR-145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma.The controversial role of phospholipase C epsilon (PLCε) in cancer development and progression.Genetic variation and gastric cancer risk: a field synopsis and meta-analysis.PLCε signaling in cancer.U-73122 reduces the cell growth in cultured MG-63 ostesarcoma cell line involving Phosphoinositide-specific Phospholipases C.Modeling K-Ras-driven lung adenocarcinoma in mice: preclinical validation of therapeutic targets.Ezrin silencing remodulates the expression of Phosphoinositide-specific Phospholipase C enzymes in human osteosarcoma cell lines Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.Ezrin-related Phosphoinositide pathway modifies RhoA and Rac1 in human osteosarcoma cell lines.PLCε1 regulates SDF-1α-induced lymphocyte adhesion and migration to sites of inflammation.A membrane-associated, fluorogenic reporter for mammalian phospholipase C isozymes.Functional role of PLCE1 intronic insertion variant associated with susceptibility to esophageal squamous-cell carcinoma.Screening and quantification of anticancer compounds in traditional Chinese medicine by hollow fiber cell fishing and hollow fiber liquid/solid-phase microextraction.The Role of Phospholipase C Signaling in Macrophage-Mediated Inflammatory Response

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Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancers.

http://www.wikidata.org/entity/Q37660073

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 03 March 2014

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancers.

@en

Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancers.

@nl

type

label

Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancers.

@en

Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancers.

@nl

prefLabel

Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancers.

@en

Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancers.

@nl

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PNAS.1311500111

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Proceedings of the National Academy of Sciences of the United States of America

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Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancers.

@en

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Afshan McCarthy

http://www.w3.org/2001/XMLSchema#string

Lorenza Magno

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Marta Martins

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Matilda Katan

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Mona El-Bahrawy

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Nicoletta Kessaris

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Philipp Yu

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Rhona Baxendale

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Sabrina Guichard

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P2860

Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling

Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice

A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma.

The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer.

RAS oncogenes: weaving a tumorigenic web

Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

New outbred colony derived from Mus musculus castaneus to identify skin tumor susceptibility loci.

Phospholipase C isozymes are deregulated in colorectal cancer--insights gained from gene set enrichment analysis of the transcriptome.

Structural and mechanistic insights into ras association domains of phospholipase C epsilon.

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4239-4244

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scholarly article

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10.1073/PNAS.1311500111

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11

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111

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2014-03-03T00:00:00Z

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260486368

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24591640

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3964118

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