Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase

Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase

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http://www.wikidata.org/entity/Q37668786
Biosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acidA high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation.Minireview: 12-Lipoxygenase and Islet β-Cell Dysfunction in Diabetes.First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis.Selective inhibition of 12-lipoxygenase protects islets and beta cells from inflammatory cytokine-mediated beta cell dysfunction.Targeting 12-lipoxygenase as a novel strategy to combat the effects of inflammation on beta cells in diabetes.New Concepts and Mechanisms of Platelet Activation Signaling.Expression pattern of 12-lipoxygenase in human islets with type 1 diabetes and type 2 diabetes12-Lipoxygenase Inhibitor Improves Functions of Cytokine-Treated Human Islets and Type 2 Diabetic Islets.An ALOX12-12-HETE-GPR31 signaling axis is a key mediator of hepatic ischemia-reperfusion injury.Ruthenium(ii) arene NSAID complexes: inhibition of cyclooxygenase and antiproliferative activity against cancer cell lines.Lipid metabolic reprogramming in hepatic ischemia-reperfusion injury.Molecular mechanisms of nonalcoholic fatty liver disease: Potential role for 12-lipoxygenase.
P2860

Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase

Item
http://www.wikidata.org/entity/Q37668786
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 06 January 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Synthesis and structure-activity relationship studies of 4-
@nl
Synthesis and structure-activi ...... inhibitors of 12-lipoxygenase
@en
type
label
Synthesis and structure-activity relationship studies of 4-
@nl
Synthesis and structure-activi ...... inhibitors of 12-lipoxygenase
@en
prefLabel
Synthesis and structure-activity relationship studies of 4-
@nl
Synthesis and structure-activi ...... inhibitors of 12-lipoxygenase
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Synthesis and structure-activi ...... inhibitors of 12-lipoxygenase
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932