First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis.

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Platelet Signaling Pathways and New Inhibitors.Novel aspects of antiplatelet therapy in cardiovascular disease Protective Effects of a Polyphenol-Rich Extract from (L.) Skeels Leaf on Oxidative Stress-Induced Diabetic Rats

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P2860

First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis.

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2017 nî lūn-bûn

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First Selective 12-LOX Inhibit ...... Minimal Effects on Hemostasis.

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First Selective 12-LOX Inhibit ...... Minimal Effects on Hemostasis.

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First Selective 12-LOX Inhibit ...... Minimal Effects on Hemostasis.

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P1476

First Selective 12-LOX Inhibit ...... Minimal Effects on Hemostasis.

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Abigail Green

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Benjamin E Tourdot

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David J Maloney

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Diane K Luci

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Jennifer Yeung

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John Cody Freedman

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Katherine Mast

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Michael Holinstat

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Reheman Adili

http://www.w3.org/2001/XMLSchema#string

Theodore R Holman

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P2860

Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells

Novel mouse hemostasis model for real-time determination of bleeding time and hemostatic plug composition.

Identification of the orphan G protein-coupled receptor GPR31 as a receptor for 12-(S)-hydroxyeicosatetraenoic acid

Increased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenase

Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation.

Thrombin-activated human platelets acutely generate oxidized docosahexaenoic-acid-containing phospholipids via 12-lipoxygenase.

Lipoxygenase inhibitors as potential cancer chemopreventives.

Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.

Protease-activated receptor signaling in platelets activates cytosolic phospholipase A2α differently for cyclooxygenase-1 and 12-lipoxygenase catalysis.

Platelets in atherothrombosis.

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scholarly article

P356

10.1161/ATVBAHA.117.309868

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English

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Ajit Jadhav

Anton Simeonov

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2017-08-03T00:00:00Z

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28775075

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5620123

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First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis.

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P2860

P2860

First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis.

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