Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells.
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Indirubin and Indirubin Derivatives for Counteracting Proliferative DiseasesTherapeutic modulators of STAT signalling for human diseasesOSU-A9 inhibits pancreatic cancer cell lines by modulating p38-JAK-STAT3 signalingTranscription Factor STAT3 as a Novel Molecular Target for Cancer Prevention.Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivoTargeting constitutively-activated STAT3 in hypoxic ovarian cancer, using a novel STAT3 inhibitorProtein kinase C zeta regulates human pancreatic cancer cell transformed growth and invasion through a STAT3-dependent mechanismEnhancing effects of indirubin on the arsenic disulfide-induced apoptosis of human diffuse large B-cell lymphoma cellsCaveolin-1 is Associated with Tumor Progression and Confers a Multi-Modality Resistance Phenotype in Pancreatic Cancer.Small-molecule induction of phospho-eIF4E sumoylation and degradation via targeting its phosphorylated serine 209 residue.Single agent BMS-911543 Jak2 inhibitor has distinct inhibitory effects on STAT5 signaling in genetically engineered mice with pancreatic cancerIntrinsic basal and luminal subtypes of muscle-invasive bladder cancer.Indirubin derivatives: a patent review (2010 - present).MYC in pancreatic cancer: novel mechanistic insights and their translation into therapeutic strategies.Natural compounds for pediatric cancer treatment.Deoxyelephantopin and Isodeoxyelephantopin as Potential Anticancer Agents with Effects on Multiple Signaling Pathways.Signal transducer and activator of transcription 3 as a therapeutic target for cancer and the tumor microenvironment.The Role of Indirubins in Inflammation and Associated Tumorigenesis.Combined inhibition of Notch and JAK/STAT is superior to monotherapies and impairs pancreatic cancer progression.Jak1/Stat3 is an upstream signaling of NF-κB activation in Helicobacter pylori-induced IL-8 production in gastric epithelial AGS cells.Induction of atypical cell death in thyroid carcinoma cells by the indirubin derivative 7-bromoindirubin-3'-oxime (7BIO).Santamarine Inhibits NF-кB and STAT3 Activation and Induces Apoptosis in HepG2 Liver Cancer Cells via Oxidative Stress.Indirubin suppresses ovarian cancer cell viabilities through the STAT3 signaling pathway
P2860
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P2860
Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Dual inhibition of Janus and S ...... human pancreatic cancer cells.
@en
Dual inhibition of Janus and S ...... human pancreatic cancer cells.
@nl
type
label
Dual inhibition of Janus and S ...... human pancreatic cancer cells.
@en
Dual inhibition of Janus and S ...... human pancreatic cancer cells.
@nl
prefLabel
Dual inhibition of Janus and S ...... human pancreatic cancer cells.
@en
Dual inhibition of Janus and S ...... human pancreatic cancer cells.
@nl
P2093
P2860
P1433
P1476
Dual inhibition of Janus and S ...... human pancreatic cancer cells.
@en
P2093
Andreas Herrmann
Anne Schroeder
Hongzhi Li
Karl-Heinz Merz
Richard Jove
Sangkil Nam
Xinlai Cheng
Yate-Ching Yuan
P2860
P304
P356
10.1016/J.MOLONC.2012.10.013
P577
2012-11-16T00:00:00Z