Base excision repair of oxidative DNA damage coupled with removal of a CAG repeat hairpin attenuates trinucleotide repeat expansion.
about
Modulation of trinucleotide repeat instability by DNA polymerase β polymorphic variant R137Q.A 5', 8-cyclo-2'-deoxypurine lesion induces trinucleotide repeat deletion via a unique lesion bypass by DNA polymerase βRepeat instability during DNA repair: Insights from model systemsAP endonuclease 1 prevents trinucleotide repeat expansion via a novel mechanism during base excision repair.Rate-determining Step of Flap Endonuclease 1 (FEN1) Reflects a Kinetic Bias against Long Flaps and Trinucleotide Repeat Sequences.Proliferating cell nuclear antigen prevents trinucleotide repeat expansions by promoting repeat deletion and hairpin removal.An oxidized abasic lesion inhibits base excision repair leading to DNA strand breaks in a trinucleotide repeat tract.The DNA damage response (DDR) is induced by the C9orf72 repeat expansion in amyotrophic lateral sclerosis.Pyrimidine Nucleosides with a Reactive (β-Chlorovinyl)sulfone or (β-Keto)sulfone Group at the C5 Position, Their Reactions with Nucleophiles and Electrophiles, and Their Polymerase-Catalyzed Incorporation into DNA.The deoxyribose phosphate lyase of DNA polymerase β suppresses a processive DNA synthesis to prevent trinucleotide repeat instability
P2860
Q33643405-2BE0F1AF-654B-4754-9B1B-3C95D8829C80Q34712058-AA34E872-240E-483C-95EB-BF4AAB1577C8Q35680075-CE053AB4-C931-434B-B536-52D9CABCCB87Q35842536-5C9FD087-C657-4A26-9EE7-F820B27E9DD0Q35978312-0B70341B-DDAC-468A-A00E-188C3546029CQ37677271-A84F6190-05F7-4B5D-875F-B7383B0B60E9Q47546931-266DA4B6-D082-4485-9319-19A5D003AD9AQ51015194-594C540A-5862-4B78-A3BD-8E9F6515E9A8Q55002715-212A3BCF-FD9F-409E-BA8D-C3A877C942ACQ58802639-11D7A701-23A6-4C5A-8477-2248F259FA5B
P2860
Base excision repair of oxidative DNA damage coupled with removal of a CAG repeat hairpin attenuates trinucleotide repeat expansion.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 14 January 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Base excision repair of oxidat ...... rinucleotide repeat expansion.
@en
Base excision repair of oxidat ...... rinucleotide repeat expansion.
@nl
type
label
Base excision repair of oxidat ...... rinucleotide repeat expansion.
@en
Base excision repair of oxidat ...... rinucleotide repeat expansion.
@nl
prefLabel
Base excision repair of oxidat ...... rinucleotide repeat expansion.
@en
Base excision repair of oxidat ...... rinucleotide repeat expansion.
@nl
P2093
P2860
P356
P1476
Base excision repair of oxidat ...... rinucleotide repeat expansion.
@en
P2093
Justin Torner
Yanhao Lai
Zunzhen Zhang
P2860
P304
P356
10.1093/NAR/GKT1372
P407
P50
P577
2014-01-14T00:00:00Z