Chemical or genetic Pin1 inhibition exerts potent anticancer activity against hepatocellular carcinoma by blocking multiple cancer-driving pathways.
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Inhibition of the prolyl isomerase Pin1 enhances the ability of sorafenib to induce cell death and inhibit tumor growth in hepatocellular carcinoma.MicroRNA-140-5p inhibits hepatocellular carcinoma by directly targeting the unique isomerase Pin1 to block multiple cancer-driving pathways.Pin1 facilitates isoproterenol‑induced cardiac fibrosis and collagen deposition by promoting oxidative stress and activating the MEK1/2‑ERK1/2 signal transduction pathway in rats.Generation of a cell-permeable cycloheptapeptidyl inhibitor against the peptidyl-prolyl isomerase Pin1.Pin1 inhibition exerts potent activity against acute myeloid leukemia through blocking multiple cancer-driving pathways.Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells
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Chemical or genetic Pin1 inhibition exerts potent anticancer activity against hepatocellular carcinoma by blocking multiple cancer-driving pathways.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 06 March 2017
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Chemical or genetic Pin1 inhib ...... tiple cancer-driving pathways.
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Chemical or genetic Pin1 inhib ...... tiple cancer-driving pathways.
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type
label
Chemical or genetic Pin1 inhib ...... tiple cancer-driving pathways.
@en
Chemical or genetic Pin1 inhib ...... tiple cancer-driving pathways.
@nl
prefLabel
Chemical or genetic Pin1 inhib ...... tiple cancer-driving pathways.
@en
Chemical or genetic Pin1 inhib ...... tiple cancer-driving pathways.
@nl
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Chemical or genetic Pin1 inhib ...... tiple cancer-driving pathways.
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P2093
Arina Li Zhang
Champ Peng Chen
Dayun Yang
Huijuan Xu
Kun Ping Lu
Mei-Qing Li
Qing-Song Chu
Ting-Fen Tsai
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P2888
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10.1038/SREP43639
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2017-03-06T00:00:00Z
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1084131550