Structure-based design of novel human Pin1 inhibitors (I)
about
Epigallocatechin-gallate Suppresses Tumorigenesis by Directly Targeting Pin1Membrane permeable cyclic peptidyl inhibitors against human Peptidylprolyl Isomerase Pin1.Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2009.Prolyl isomerase Pin1 acts downstream of miR200c to promote cancer stem-like cell traits in breast cancerPin1-mediated Sp1 phosphorylation by CDK1 increases Sp1 stability and decreases its DNA-binding activity during mitosis.New Frontiers in DruggabilityRoles of Prolyl Isomerases in RNA-Mediated Gene ExpressionPin1 protein regulates Smad protein signaling and pulmonary fibrosis.Pin1 is related with clinical stage of papillary thyroid carcinoma.Template-induced macrocycle diversity through large ring-forming alkylations of tryptophan.The prolyl isomerase pin1 regulates mRNA levels of genes with short half-lives by targeting specific RNA binding proteinsChemical or genetic Pin1 inhibition exerts potent anticancer activity against hepatocellular carcinoma by blocking multiple cancer-driving pathways.Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease.Hsp90-binding immunophilins as a potential new platform for drug treatment.The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target.Peptidyl-Proline Isomerases (PPIases): Targets for Natural Products and Natural Product-Inspired Compounds.The quest for novel chemical matter and the contribution of computer-aided de novo design.Prolyl isomerase Pin1: a promoter of cancer and a target for therapyGears-In-Motion: The Interplay of WW and PPIase Domains in Pin1
P2860
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P2860
Structure-based design of novel human Pin1 inhibitors (I)
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structure-based design of novel human Pin1 inhibitors (I)
@ast
Structure-based design of novel human Pin1 inhibitors (I)
@en
Structure-based design of novel human Pin1 inhibitors (I)
@nl
type
label
Structure-based design of novel human Pin1 inhibitors (I)
@ast
Structure-based design of novel human Pin1 inhibitors (I)
@en
Structure-based design of novel human Pin1 inhibitors (I)
@nl
prefLabel
Structure-based design of novel human Pin1 inhibitors (I)
@ast
Structure-based design of novel human Pin1 inhibitors (I)
@en
Structure-based design of novel human Pin1 inhibitors (I)
@nl
P2093
P3181
P1476
Structure-based design of novel human Pin1 inhibitors (I)
@en
P2093
Barbara Mroczkowski
Chuangxing Guo
David Matthews
Eleanor Dagostino
Gerrit Los
Hans Parge
Ian Popoff
James Thomson
Joseph Marakovits
Joseph Piraino
P304
P3181
P356
10.1016/J.BMCL.2009.08.034
P407
P577
2009-08-13T00:00:00Z