Distinct cell types control lymphoid subset development by means of IL-15 and IL-15 receptor alpha expression.
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Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteinsIL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in celiac disease-associated inflammation and lymphomagenesisRegulating the immune system via IL-15 transpresentationRole of the intestinal cytokine microenvironment in shaping the intraepithelial lymphocyte repertoireGeneration of a novel regulatory NK cell subset from peripheral blood CD34+ progenitors promoted by membrane-bound IL-15Plasmid-encoded interleukin-15 receptor alpha enhances specific immune responses induced by a DNA vaccine in vivo.Combined IL-15/IL-15Ralpha immunotherapy maximizes IL-15 activity in vivo.IL-15: a central regulator of celiac disease immunopathology.Homeostatic defects in interleukin 18-deficient mice contribute to protection against the lethal effects of endotoxin.{gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cells.In vivo role of Flt3 ligand and dendritic cells in NK cell homeostasisThymic and peripheral microenvironments differentially mediate development and maturation of iNKT cells by IL-15 transpresentation.CD4+ T cells are required for the maintenance, not programming, of memory CD8+ T cells after acute infection.Expression of IL-15RA or an IL-15/IL-15RA fusion on CD8+ T cells modifies adoptively transferred T-cell function in cisCX3CR1 signaling on monocytes is dispensable after intracerebral hemorrhageIntraepithelial lymphocytes: to serve and protect.The IL-15/IL-15Ralpha on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cellsIncreased serum soluble IL-15Rα levels in T-cell large granular lymphocyte leukemiaIRF-1 promotes liver transplant ischemia/reperfusion injury via hepatocyte IL-15/IL-15Rα productionTrafficking of circulating pro-NK cells to the decidualizing uterus: regulatory mechanisms in the mouse and humanCutting edge: the role of IFN-α receptor and MyD88 signaling in induction of IL-15 expression in vivo.Selective reduction of post-selection CD8 thymocyte proliferation in IL-15Rα deficient mice.Trans-presentation of donor-derived interleukin 15 is necessary for the rapid onset of acute graft-versus-host disease but not for graft-versus-tumor activity.Gamma c cytokines condition the progressive differentiation of CD4+ T cellsSarcopenia, obesity, and natural killer cell immune senescence in aging: altered cytokine levels as a common mechanismCoordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasisHuman natural killer cell development.Mouse fetal and embryonic liver cells differentiate human umbilical cord blood progenitors into CD56-negative natural killer cell precursors in the absence of interleukin-15A retrospective on the requirements for gammadelta T-cell development.The thymus chapter in the life of gut-specific intra epithelial lymphocytes.An activation-induced IL-15 isoform is a natural antagonist for IL-15 function.Transcription factor KLF2 regulates homeostatic NK cell proliferation and survival.Dendritic cells drive memory CD8 T-cell homeostasis via IL-15 transpresentationExogenous IL-15 in combination with IL-15R alpha rescues natural killer cells from apoptosis induced by chronic alcohol consumption.Uneven colonization of the lymphoid periphery by T cells that undergo early TCR{alpha} rearrangements.Functions of γC cytokines in immune homeostasis: current and potential clinical applications.TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage.Characterization of the IL-15 niche in primary and secondary lymphoid organs in vivo.Trans-presentation: a novel mechanism regulating IL-15 delivery and responses.SAP-Dependent and -Independent Regulation of Innate T Cell Development Involving SLAMF Receptors.
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Distinct cell types control lymphoid subset development by means of IL-15 and IL-15 receptor alpha expression.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Distinct cell types control ly ...... -15 receptor alpha expression.
@en
Distinct cell types control ly ...... -15 receptor alpha expression.
@nl
type
label
Distinct cell types control ly ...... -15 receptor alpha expression.
@en
Distinct cell types control ly ...... -15 receptor alpha expression.
@nl
prefLabel
Distinct cell types control ly ...... -15 receptor alpha expression.
@en
Distinct cell types control ly ...... -15 receptor alpha expression.
@nl
P2093
P2860
P356
P1476
Distinct cell types control ly ...... -15 receptor alpha expression.
@en
P2093
Arturo Cabrera-Hernandez
Elizabeth C Nowak
Hector L Aguila
Kimberly S Schluns
Leo Lefrançois
Lynn Puddington
P2860
P304
P356
10.1073/PNAS.0307442101
P407
P577
2004-04-01T00:00:00Z