Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope.
about
Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) responseHIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBECMutational escape from CD8+ T cell immunity: HCV evolution, from chimpanzees to manStable Cytotoxic T Cell Escape Mutation in Hepatitis C Virus Is Linked to Maintenance of Viral FitnessConstraints on HIV-1 diversity from protein structureHLA alleles associated with slow progression to AIDS truly prefer to present HIV-1 p24.HIV-1 group M conserved elements vaccine.Transmission of HIV-1 CTL escape variants provides HLA-mismatched recipients with a survival advantage.Phylogenetic dependency networks: inferring patterns of CTL escape and codon covariation in HIV-1 Gag.Simian immunodeficiency virus and human immunodeficiency virus type 1 matrix proteins specify different capabilities to modulate B cell growth.Immune escape mutations detected within HIV-1 epitopes associated with viral control during treatment interruptionHIV-1 Transmission, Replication Fitness and Disease Progression.Dynamics of haplotype frequency change in a CD8+TL epitope of simian immunodeficiency virus.Functional constraints of influenza A virus epitopes limit escape from cytotoxic T lymphocytesUse of molecular beacons for rapid, real-time, quantitative monitoring of cytotoxic T-lymphocyte epitope mutations in simian immunodeficiency virusDe novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infectionBacteria modulate the CD8+ T cell epitope repertoire of host cytosol-exposed proteins to manipulate the host immune response.Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolutionEarly selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infectionHuman immunodeficiency virus type 1 coreceptor switching: V1/V2 gain-of-fitness mutations compensate for V3 loss-of-fitness mutations.Vaccination reduces simian-human immunodeficiency virus sequence reversion through enhanced viral controlHIV-1 p24(gag) derived conserved element DNA vaccine increases the breadth of immune response in mice.Compensatory substitutions restore normal core assembly in simian immunodeficiency virus isolates with Gag epitope cytotoxic T-lymphocyte escape mutations.Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infectionEvolutionary gamut of in vivo Gag substitutions during early HIV-1 subtype C infection.Pyrosequencing reveals restricted patterns of CD8+ T cell escape-associated compensatory mutations in simian immunodeficiency virus.Rapid reversion of sequence polymorphisms dominates early human immunodeficiency virus type 1 evolution.The antiviral efficacy of simian immunodeficiency virus-specific CD8+ T cells is unrelated to epitope specificity and is abrogated by viral escape.CD8(+) T-cell Cytotoxic Capacity Associated with Human Immunodeficiency Virus-1 Control Can Be Mediated through Various Epitopes and Human Leukocyte Antigen TypesImmune-mediated attenuation of HIV-1Gag-specific CD8+ T lymphocytes recognize infected cells before AIDS-virus integration and viral protein expression.Role of human immunodeficiency virus (HIV)-specific T-cell immunity in control of dual HIV-1 and HIV-2 infection.Uncommon pathways of immune escape attenuate HIV-1 integrase replication capacity.Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replicationEscape and compensation from early HLA-B57-mediated cytotoxic T-lymphocyte pressure on human immunodeficiency virus type 1 Gag alter capsid interactions with cyclophilin A.Conservation of HIV-1 T cell epitopes across time and clades: validation of immunogenic HLA-A2 epitopes selected for the GAIA HIV vaccineTargeting of conserved gag-epitopes in early HIV infection is associated with lower plasma viral load and slower CD4(+) T cell depletion.HLA class I-driven evolution of human immunodeficiency virus type 1 subtype c proteome: immune escape and viral load.A comprehensive analysis of the naturally occurring polymorphisms in HIV-1 Vpr: potential impact on CTL epitopesIdentification of immunogenic HLA-B7 "Achilles' heel" epitopes within highly conserved regions of HIV
P2860
Q21131580-A026DCCD-4036-414B-8A8D-9EA73DA2CD33Q21559422-D6C68CF6-4065-4FC7-B81D-DEABDF891BA3Q27485215-A87AF1B2-FEC4-4B88-A052-3E50EE28F993Q27486654-C804DB42-6832-4FCF-9D59-35D65A82097AQ30394299-D8A5970A-ECCD-491D-A2E6-E427601A5C57Q33299493-77821617-31A2-414C-9240-E582E2B7E711Q33308246-25F42D3E-CFC5-408A-8A48-5394F7977710Q33325923-404CBFA6-D86F-4D46-8FAA-2E314FAFD9FBQ33385995-7638C6A9-06F5-42A6-A454-3101E30F787CQ33602706-94849678-4964-48FE-B84D-B2CC5E035069Q33745356-B2B36F5E-CE64-4C28-AAC5-D775F15C7CBEQ33758570-10E1EBAC-2216-4D0C-9297-1790F2C74694Q33824415-757B82C3-C757-4215-B67A-C198ECA0724CQ33930372-BA31229B-37B3-434F-A8ED-89558752816EQ34042364-70FA1BFA-3FEC-484D-816F-643D2F673C76Q34045616-0F641AF8-ADFB-4C91-AD82-7B5EF6A2945CQ34055255-35EB5812-F72E-4BCC-8795-AB799F952F4AQ34092644-67EF7EF3-0551-4DCB-99E1-52783FF909F0Q34295972-A0ED6240-1436-4B76-BD2A-0D36D0E89F3DQ34301803-04852CA3-F061-4A72-91C1-5A448D3792ADQ34416586-1E073538-40A1-4B94-A9B0-4B9FDB524A6CQ34653619-2B86D2C6-6F2C-4338-B8EF-B63C54748F73Q35024004-822A030B-FDAE-4428-B4AF-C139C8D532F9Q35274776-5A0815B9-AA20-4715-88D1-61137AE8D269Q35535663-7EA01329-1B0B-4584-834F-7500B70275E5Q35599427-B43FEEA2-FD1E-440F-A49F-4ACC244C15BBQ35634318-0D1B123F-9B54-44B7-BC35-6132FD53928BQ35784928-3EB457B4-9CD3-4460-9B15-C60B4568B67BQ35797743-1BF53077-D880-4D01-8EE0-3B93428FE487Q35798108-98E60262-9B5D-4848-BD3D-DC2C3F293CA0Q35904453-7E6F01A1-4AB1-4922-84B1-B307BADA2014Q35947958-6CF2F653-B9FD-498D-896B-8369F03BC7E1Q36086711-80AA464E-ECD6-4582-82D6-B9A780C490EDQ36315510-450F4058-A9E8-49AA-BF22-5648077D0A3FQ36315572-77DD3254-35CB-4573-B332-CBF07A318A3DQ36467153-DD468362-F245-401F-B2EF-1F42FDBD3D53Q36634956-577E924D-2B41-4B31-89E6-038C48E85511Q36748059-7611C9A8-556B-478F-8902-BD0CA49E9ADFQ36908259-3BB91F00-06E0-41A1-9EDE-DFA9C7662A90Q36910003-C2A472C2-68F8-4674-86BB-C2051EB9BDD5
P2860
Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Fitness costs limit viral esca ...... ucturally constrained epitope.
@en
Fitness costs limit viral esca ...... ucturally constrained epitope.
@nl
type
label
Fitness costs limit viral esca ...... ucturally constrained epitope.
@en
Fitness costs limit viral esca ...... ucturally constrained epitope.
@nl
prefLabel
Fitness costs limit viral esca ...... ucturally constrained epitope.
@en
Fitness costs limit viral esca ...... ucturally constrained epitope.
@nl
P2093
P2860
P1433
P1476
Fitness costs limit viral esca ...... ucturally constrained epitope.
@en
P2093
Dan H Barouch
Fred W Peyerl
Heidi S Bazick
Michael H Newberg
Norman L Letvin
P2860
P304
13901-13910
P356
10.1128/JVI.78.24.13901-13910.2004
P407
P577
2004-12-01T00:00:00Z