53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation. - Wikidata - awgldk - TriplyDB

53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation.

53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation.

http://www.wikidata.org/entity/Q37684399

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53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition.CD8 Memory Cells Develop Unique DNA Repair Mechanisms Favoring Productive Division Expression of DNA damage checkpoint 53BP1 is correlated with prognosis, cell proliferation and apoptosis in colorectal cancer.Novel targets for ATM-deficient malignancies.Common and unique genetic interactions of the poly(ADP-ribose) polymerases PARP1 and PARP2 with DNA double-strand break repair pathways.53BP1 loss induces chemoresistance of colorectal cancer cells to 5-fluorouracil by inhibiting the ATM-CHK2-P53 pathway.Monitoring DNA Repair Consequences of ATM Signaling Using Simultaneous Fluorescent Readouts.

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53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation.

http://www.wikidata.org/entity/Q37684399

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 15 July 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

53BP1 is limiting for NHEJ rep ...... oncogenic stress or radiation.

@en

53BP1 is limiting for NHEJ rep ...... oncogenic stress or radiation.

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type

label

53BP1 is limiting for NHEJ rep ...... oncogenic stress or radiation.

@en

53BP1 is limiting for NHEJ rep ...... oncogenic stress or radiation.

@nl

prefLabel

53BP1 is limiting for NHEJ rep ...... oncogenic stress or radiation.

@en

53BP1 is limiting for NHEJ rep ...... oncogenic stress or radiation.

@nl

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Molecular Cancer Research

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53BP1 is limiting for NHEJ rep ...... oncogenic stress or radiation.

@en

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David L Huso

http://www.w3.org/2001/XMLSchema#string

Ivana Rybanska-Spaeder

http://www.w3.org/2001/XMLSchema#string

Jeremy Chou

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Mansi Prakash

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Sonia Franco

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Stephen Desiderio

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Tameca Jefferson

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Taylor L Reynolds

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P2860

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

The DNA-damage response in human biology and disease

Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes

The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo.

53BP1 regulates DSB repair using Rif1 to control 5' end resection

A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice.

The DNA damage response: ten years after

ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

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1223-1234

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scholarly article

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10.1158/1541-7786.MCR-13-0252-T

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10

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2013-07-15T00:00:00Z

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23858098

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3975592

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