DACT2 silencing by promoter CpG methylation disrupts its regulation of epithelial-to-mesenchymal transition and cytoskeleton reorganization in breast cancer cells.
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Epigenetic silencing of ADAMTS18 promotes cell migration and invasion of breast cancer through AKT and NF-κB signalingMethylation of DACT2 promotes breast cancer development by activating Wnt signalingUpregulation of DACT2 suppresses proliferation and enhances apoptosis of glioma cell via inactivation of YAP signaling pathwayThe tumor suppressor interferon regulatory factor 8 inhibits β-catenin signaling in breast cancers, but is frequently silenced by promoter methylationManganese-12 acetate suppresses the migration, invasion, and epithelial-mesenchymal transition by inhibiting Wnt/β-catenin and PI3K/AKT signaling pathways in breast cancer cells.Targeting the Epigenome as a Novel Therapeutic Approach for Breast Cancer.LncRNAs regulate the cytoskeleton and related Rho/ROCK signaling in cancer metastasis.The new 6q27 tumor suppressor DACT2, frequently silenced by CpG methylation, sensitizes nasopharyngeal cancer cells to paclitaxel and 5-FU toxicity via β-catenin/Cdc25c signaling and G2/M arrest
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P2860
DACT2 silencing by promoter CpG methylation disrupts its regulation of epithelial-to-mesenchymal transition and cytoskeleton reorganization in breast cancer cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 29 September 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
DACT2 silencing by promoter Cp ...... zation in breast cancer cells.
@en
DACT2 silencing by promoter Cp ...... zation in breast cancer cells.
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type
label
DACT2 silencing by promoter Cp ...... zation in breast cancer cells.
@en
DACT2 silencing by promoter Cp ...... zation in breast cancer cells.
@nl
prefLabel
DACT2 silencing by promoter Cp ...... zation in breast cancer cells.
@en
DACT2 silencing by promoter Cp ...... zation in breast cancer cells.
@nl
P2093
P2860
P356
P1433
P1476
DACT2 silencing by promoter Cp ...... ization in breast cancer cells
@en
P2093
Chunhong Li
Guosheng Ren
Kathleen Kelly
Michael Oberst
Tingxiu Xiang
Weiyan Peng
Yichao Fan
P2860
P304
70924-70935
P356
10.18632/ONCOTARGET.12341
P407
P50
P577
2016-10-01T00:00:00Z