Selective propagation of functional mitochondrial DNA during oogenesis restricts the transmission of a deleterious mitochondrial variant.
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Keeping mtDNA in shape between generationsEvolutionary defined role of the mitochondrial DNA in fertility, disease and ageingGenetic Evidence for Elevated Pathogenicity of Mitochondrial DNA Heteroplasmy in Autism Spectrum DisorderMitochondrial DNA disease and developmental implications for reproductive strategiesSegregation of Naturally Occurring Mitochondrial DNA Variants in a Mini-Pig ModelElectron tomographic analysis reveals ultrastructural features of mitochondrial cristae architecture which reflect energetic state and aging.Mitogenomes of polar bodies and corresponding oocytes.The coevolutionary period of Wolbachia pipientis infecting Drosophila ananassae and its impact on the evolution of the host germline stem cell regulating genesMaternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA.Why are most organelle genomes transmitted maternally?Genetic mosaic analysis of a deleterious mitochondrial DNA mutation in Drosophila reveals novel aspects of mitochondrial regulation and function.On the adaptive value of cytoplasmic genomes in plants.The cAMP phosphodiesterase Prune localizes to the mitochondrial matrix and promotes mtDNA replication by stabilizing TFAM.Mitochondrial maintenance failure in aging and role of sexual dimorphism.Mitochondrial activity in gametes and transmission of viable mtDNASelection on Mitochondrial Variants Occurs between and within Individuals in an Expanding Invasion.Heritable symbiosis: The advantages and perils of an evolutionary rabbit hole.Selections that isolate recombinant mitochondrial genomes in animals.Loss of Drosophila i-AAA protease, dYME1L, causes abnormal mitochondria and apoptotic degeneration.Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies.Acknowledging selection at sub-organismal levels resolves controversy on pro-cooperation mechanisms.Transmission of human mtDNA heteroplasmy in the Genome of the Netherlands families: support for a variable-size bottleneck.p53 as guardian of the mitochondrial genomeThe mitochondrial outer membrane protein MDI promotes local protein synthesis and mtDNA replicationSelfish drive can trump function when animal mitochondrial genomes compete.In Situ Labeling of Mitochondrial DNA Replication in Drosophila Adult Ovaries by EdU StainingSelective removal of deletion-bearing mitochondrial DNA in heteroplasmic Drosophila.Mitochondrial Heteroplasmy.Mitochondrial DNA heteroplasmy in human health and disease.Heteroplasmic shifts in tumor mitochondrial genomes reveal tissue-specific signals of relaxed and positive selection.Intra-individual purifying selection on mitochondrial DNA variants during human oogenesis.Cellular and population level processes influence the rate, accumulation and observed frequency of inherited and somatic mtDNA mutations.Selection of mitochondria in female germline cells: is Balbiani body implicated in this process?Evolutionary and Functional Mitogenomics Associated With the Genetic Restoration of the Florida Panther.Heteroplasmy due to coexistence of mtCOI haplotypes from different lineages of the Thrips tabaci cryptic species group.Long Oskar Controls Mitochondrial Inheritance in Drosophila melanogaster.Evolutionary implications of mitochondrial genetic variation: mitochondrial genetic effects on OXPHOS respiration and mitochondrial quantity change with age and sex in fruit flies.Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos.Proliferation Cycle Causes Age Dependent Mitochondrial Deficiencies and Contributes to the Aging of Stem Cells.Incompatibility between mitochondrial and nuclear genomes during oogenesis results in ovarian failure and embryonic lethality.
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Selective propagation of functional mitochondrial DNA during oogenesis restricts the transmission of a deleterious mitochondrial variant.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 09 March 2014
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Selective propagation of funct ...... terious mitochondrial variant.
@en
Selective propagation of funct ...... terious mitochondrial variant.
@nl
type
label
Selective propagation of funct ...... terious mitochondrial variant.
@en
Selective propagation of funct ...... terious mitochondrial variant.
@nl
prefLabel
Selective propagation of funct ...... terious mitochondrial variant.
@en
Selective propagation of funct ...... terious mitochondrial variant.
@nl
P2093
P2860
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P1476
Selective propagation of funct ...... terious mitochondrial variant.
@en
P2093
P2860
P2888
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P356
10.1038/NG.2920
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P577
2014-03-09T00:00:00Z