"Exon-shuffling" maps control of antibody- and T-cell-recognition sites to the NH2-terminal domain of the class II major histocompatibility polypeptide A beta.
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Sequence and evolution of HLA-DR7- and -DRw53-associated beta-chain genesHLA Mismatching Strategies for Solid Organ Transplantation - A Balancing ActCytoplasmic domain affects membrane expression and function of an Ia molecule.Point mutations define positions in HLA-DR3 molecules that affect antigen presentation.Immune deficiency due to high copy numbers of an Ak beta transgene.Nucleotide substitution at major histocompatibility complex class II loci: evidence for overdominant selection.The mouse E beta 2 gene: a class II MHC beta gene with limited intraspecies polymorphism and an unusual pattern of transcription.Genetic analysis of the imperfect association of H-2 haplotype with lupus-like autoimmune disease.Localization of a critical restriction site on the I-A beta chain that determines susceptibility to collagen-induced arthritis in mice.Predominant role of amino-terminal sequences in dictating efficiency of class II major histocompatibility complex alpha beta dimer expression.Expression of human class II major histocompatibility complex antigens using retrovirus vectors.Allele-specific control of Ia molecule surface expression and conformation: implications for a general model of Ia structure-function relationshipsIntramolecular polyspecificity in CD4 T-cell recognition of Ad-restricted epitopes of proteoglycan aggrecan.Identification of functional regions on the I-Ab molecule by site-directed mutagenesis.Identification of a T-helper cell epitope on the rotavirus VP6 protein.Presentation of antigen by mixed isotype class II molecules in normal H-2d mice.Regulation of antigen presentation by acidic pH.I-A-restricted T cell antigen recognition. Analysis of the roles of A alpha and A beta using DNA-mediated gene transfer.Imbalanced MHC class II molecule expression at surface of murine B cell lymphomasFunctional analysis of influenza-specific helper T cell clones in vivo. T cells specific for internal viral proteins provide cognate help for B cell responses to hemagglutinin.Identification of an immunodominant region on the I-A beta chain using site-directed mutagenesis and DNA-mediated gene transfer.Structural mutation affecting intracellular transport and cell surface expression of murine class II moleculesA beta polymorphic residues responsible for class II molecule recognition by alloreactive T cells.Diversity of the class II (I-Ak/I-Ek)-restricted T cell repertoire for influenza hemagglutinin and antigenic drift. Six nonoverlapping epitopes on the HA1 subunit are defined by synthetic peptides.DNA sequence analysis of I-Ak beta mutants reveals serologically immunodominant region.Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupusHeterogeneity of single cell cytokine gene expression in clonal T cell populations.T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosusIdentification of eight determinants in the hemagglutinin molecule of influenza virus A/PR/8/34 (H1N1) which are recognized by class II-restricted T cells from BALB/c mice.Cellular and peptide requirements for in vitro clonal deletion of immature thymocytes.Induction of Graves-like disease in mice by immunization with fibroblasts transfected with the thyrotropin receptor and a class II moleculeCytokines, IgG subclasses and costimulation in a mouse model of thyroid autoimmunity induced by injection of fibroblasts co-expressing MHC class II and thyroid autoantigens.Lack of female bias in a mouse model of autoimmune hyperthyroidism (Graves' disease).Degenerate self-reactive human T-cell receptor causes spontaneous autoimmune disease in mice.
P2860
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P2860
"Exon-shuffling" maps control of antibody- and T-cell-recognition sites to the NH2-terminal domain of the class II major histocompatibility polypeptide A beta.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1985
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
"Exon-shuffling" maps control ...... patibility polypeptide A beta.
@en
"Exon-shuffling" maps control ...... patibility polypeptide A beta.
@nl
type
label
"Exon-shuffling" maps control ...... patibility polypeptide A beta.
@en
"Exon-shuffling" maps control ...... patibility polypeptide A beta.
@nl
prefLabel
"Exon-shuffling" maps control ...... patibility polypeptide A beta.
@en
"Exon-shuffling" maps control ...... patibility polypeptide A beta.
@nl
P2093
P2860
P356
P1476
"Exon-shuffling" maps control ...... mpatibility polypeptide A beta
@en
P2093
J D Ashwell
K M Nickerson
R I Lechler
R N Germain
P2860
P304
P356
10.1073/PNAS.82.9.2940
P407
P577
1985-05-01T00:00:00Z