Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors.
about
IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium.Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal.RABL2 interacts with the intraflagellar transport-B complex and CEP19 and participates in ciliary assembly.Practical method for targeted disruption of cilia-related genes by using CRISPR/Cas9-mediated, homology-independent knock-in system.Intraflagellar Transporter Protein 140 (IFT140), a component of IFT-A complex, is Essential for Male Fertility and Spermiogenesis in Mice.Ciliary protein trafficking mediated by IFT and BBSome complexes with the aid of kinesin-2 and dynein-2 motors.Robust interaction of IFT70 with IFT52-IFT88 in the IFT-B complex is required for ciliogenesis.BBS1 is involved in retrograde trafficking of ciliary GPCRs in the context of the BBSome complex.The molecular machines that traffic signaling receptors into and out of cilia.
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Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 December 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Intraflagellar transport-A com ...... y G protein-coupled receptors.
@en
Intraflagellar transport-A com ...... y G protein-coupled receptors.
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type
label
Intraflagellar transport-A com ...... y G protein-coupled receptors.
@en
Intraflagellar transport-A com ...... y G protein-coupled receptors.
@nl
prefLabel
Intraflagellar transport-A com ...... y G protein-coupled receptors.
@en
Intraflagellar transport-A com ...... y G protein-coupled receptors.
@nl
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Intraflagellar transport-A com ...... ry G protein-coupled receptors
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Tomoaki Hirano
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P304
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10.1091/MBC.E16-11-0813
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2016-12-08T00:00:00Z