Identification and characterization of Uss1p (Sdb23p): a novel U6 snRNA-associated protein with significant similarity to core proteins of small nuclear ribonucleoproteins.
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A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicingSm and Sm-like proteins assemble in two related complexes of deep evolutionary origin.Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like proteinStructure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesissnRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactionsStructures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like proteinCharacterization of U6 snRNA-protein interactions.Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B' and the Sm-like protein LSm4, and their interaction with the SMN protein.A conserved Lsm-interaction motif in Prp24 required for efficient U4/U6 di-snRNP formationDomains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formationThe Sm domain is an ancient RNA-binding motif with oligo(U) specificityAn Hfq-like protein in archaea: Crystal structure and functional characterization of the Sm protein from Methanococcus jannaschiiRequirements for nuclear localization of the Lsm2-8p complex and competition between nuclear and cytoplasmic Lsm complexesIdentification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometryMultiple functional interactions between components of the Lsm2-Lsm8 complex, U6 snRNA, and the yeast La proteinA role for Q/N-rich aggregation-prone regions in P-body localization.Yeast caspase 1 links messenger RNA stability to apoptosis in yeastThe box H + ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase.Functional analyses of interacting factors involved in both pre-mRNA splicing and cell cycle progression in Saccharomyces cerevisiae.The identification and characterization of a novel splicing protein, Isy1p, of Saccharomyces cerevisiae.MRN1 implicates chromatin remodeling complexes and architectural factors in mRNA maturation.Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins.Transcriptional pulse-chase analysis reveals a role for a novel snRNP-associated protein in the manufacture of spliceosomal snRNPs.Identification and characterization of Prp45p and Prp46p, essential pre-mRNA splicing factors.Snt309p, a component of the Prp19p-associated complex that interacts with Prp19p and associates with the spliceosome simultaneously with or immediately after dissociation of U4 in the same manner as Prp19p.Peri-implantation lethality in mice lacking the Sm motif-containing protein Lsm4Interactions within the yeast Sm core complex: from proteins to amino acids.Temporal and tissue specific regulation of RP-associated splicing factor genes PRPF3, PRPF31 and PRPC8--implications in the pathogenesis of RP.A role for the yeast La protein in U6 snRNP assembly: evidence that the La protein is a molecular chaperone for RNA polymerase III transcriptsFunctional characterization of nuclear localization signals in yeast Sm proteins.Identification of novel genes required for yeast pre-mRNA splicing by means of cold-sensitive mutationsAll small nuclear RNAs (snRNAs) of the [U4/U6.U5] Tri-snRNP localize to nucleoli; Identification of the nucleolar localization element of U6 snRNA.Disruption of the 5' stem-loop of yeast U6 RNA induces trimethylguanosine capping of this RNA polymerase III transcript in vivo.Mutations in the Saccharomyces cerevisiae LSM1 gene that affect mRNA decapping and 3' end protection.The yeast cytoplasmic LsmI/Pat1p complex protects mRNA 3' termini from partial degradation.Evidence for the presence of a small U5-like RNA in active trans-spliceosomes of Trypanosoma brucei.A connection between pre-mRNA splicing and the cell cycle in fission yeast: cdc28+ is allelic with prp8+ and encodes an RNA-dependent ATPase/helicaseThe decapping activator Lsm1p-7p-Pat1p complex has the intrinsic ability to distinguish between oligoadenylated and polyadenylated RNAs.Spliceosomal U snRNP core assembly: Sm proteins assemble onto an Sm site RNA nonanucleotide in a specific and thermodynamically stable mannerArabidopsis floral initiator SKB1 confers high salt tolerance by regulating transcription and pre-mRNA splicing through altering histone H4R3 and small nuclear ribonucleoprotein LSM4 methylation.
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Identification and characterization of Uss1p (Sdb23p): a novel U6 snRNA-associated protein with significant similarity to core proteins of small nuclear ribonucleoproteins.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1995
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Identification and characteriz ...... ll nuclear ribonucleoproteins.
@en
Identification and characterization of Uss1p
@nl
type
label
Identification and characteriz ...... ll nuclear ribonucleoproteins.
@en
Identification and characterization of Uss1p
@nl
prefLabel
Identification and characteriz ...... ll nuclear ribonucleoproteins.
@en
Identification and characterization of Uss1p
@nl
P2093
P2860
P1433
P1476
Identification and characteriz ...... ll nuclear ribonucleoproteins.
@en
P2093
P2860
P304
P407
P577
1995-05-01T00:00:00Z