Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas.
about
Phase II study of mTORC1 inhibition by everolimus in neurofibromatosis type 2 patients with growing vestibular schwannomas.Therapeutic advances for the tumors associated with neurofibromatosis type 1, type 2, and schwannomatosisSurgical management of giant neurofibroma in soft tissue: a single-center retrospective analysis.Recommendations for imaging tumor response in neurofibromatosis clinical trials.Comprehensive pharmacological profiling of neurofibromatosis cell lines.Activity of Selumetinib in Neurofibromatosis Type 1-Related Plexiform NeurofibromasThe NF1 gene revisited - from bench to bedside.Achieving consensus for clinical trials: the REiNS International Collaboration.Neurofibromatosis-related tumors: emerging biology and therapies.Classic Ras Proteins Promote Proliferation and Survival via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells.Sirolimus for progressive neurofibromatosis type 1-associated plexiform neurofibromas: a neurofibromatosis Clinical Trials Consortium phase II study.The Challenge of Cancer Genomics in Rare Nervous System Neoplasms: Malignant Peripheral Nerve Sheath Tumors as a Paradigm for Cross-Species Comparative Oncogenomics.Preclinical Evidence for the Use of Sunitinib Malate in the Treatment of Plexiform Neurofibromas.Long-term growth rate of vestibular schwannoma in neurofibromatosis 2: A volumetric consideration.Orbital/Periorbital Plexiform Neurofibromas in Children with Neurofibromatosis Type 1: Multidisciplinary Recommendations for Care.Phase II trial of pegylated interferon alfa-2b in young patients with neurofibromatosis type 1 and unresectable plexiform neurofibromas.Treatment of neurofibromatosis type 1.Volumetric MRI Analysis of Plexiform Neurofibromas in Neurofibromatosis Type 1: Comparison of Two Methods.Recent Advances in Intradural Spinal Tumors.Tranilast inhibits the expression of genes related to epithelial-mesenchymal transition and angiogenesis in neurofibromin-deficient cells.The Fourth International Symposium on Genetic Disorders of the Ras/MAPK pathway.
P2860
Q27853117-9289D85D-EFB0-4422-9537-233802CA3512Q30357776-E3F14BA3-2025-476B-B991-6426C23816DDQ30408140-A214110F-5B42-433C-90C8-72A7351D7FA3Q30425757-E43412D9-C149-4C4E-9CEB-087833AE1E3AQ33622690-9B46EE98-A918-488A-8A67-29AE5B043CE2Q33900906-CDBD5E29-7F8A-4EB1-882E-DDDC5E06A2D7Q34227509-16E53887-B52D-4014-8036-F61FB59C6E7BQ35046436-ABACF9F6-3B0B-440B-BD8F-4539E96F41E7Q35218073-E07B328E-0EFA-4AA0-A2A7-08F508D3B67FQ35612406-38D75135-A23A-4A75-B13D-5CD35C940BBCQ35788825-7BDC52C1-F7D6-4247-BC58-8E4FE16DBAB8Q36753692-8E7E3652-F342-45A5-922C-B9055ECE2DC9Q36887270-BF4B5B08-0DF4-4887-B3A5-B601EBB17E82Q38807760-177889F2-468D-4A55-B2B4-3F0C4766CF09Q39000307-F8B4065D-F5BD-43F5-AC98-6835C1F1AD1EQ39502676-409CA2C4-18BB-44DE-8BD2-4A81C42529F3Q41008080-BF961A41-1791-444B-A336-29E450C2A174Q47227758-390D1FB5-C280-4798-8FA5-A756106B7B0EQ50027408-1AE1F36D-8474-4BDA-8547-C1407CB8E149Q52718681-C3F1E771-B69D-4AFE-92F3-E76A3F36CE63Q53050096-F84FB2C0-5192-4163-B356-6385E12D2BEA
P2860
Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 04 February 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Phase 2 randomized, flexible c ...... ssive plexiform neurofibromas.
@en
Phase 2 randomized, flexible c ...... ssive plexiform neurofibromas.
@nl
type
label
Phase 2 randomized, flexible c ...... ssive plexiform neurofibromas.
@en
Phase 2 randomized, flexible c ...... ssive plexiform neurofibromas.
@nl
prefLabel
Phase 2 randomized, flexible c ...... ssive plexiform neurofibromas.
@en
Phase 2 randomized, flexible c ...... ssive plexiform neurofibromas.
@nl
P2093
P2860
P921
P356
P1433
P1476
Phase 2 randomized, flexible c ...... essive plexiform neurofibromas
@en
P2093
AeRang Kim
Alyssa Reddy
Andrea Gillespie
Brigitte C Widemann
Bruce R Korf
Elizabeth Fox
Jean Belasco
Jeffrey Solomon
John J Wright
P2860
P304
P356
10.1093/NEUONC/NOU004
P577
2014-02-04T00:00:00Z