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Cytoneme-mediated delivery of hedgehog regulates the expression of bone morphogenetic proteins to maintain germline stem cells in DrosophilaIncreased expression of the dyslexia candidate gene DCDC2 affects length and signaling of primary cilia in neuronsThe hedgehog receptor patched is involved in cholesterol transportRadioresistance of Brain TumorsRoles for Hedgehog signaling in adult organ homeostasis and repairShh signal and its functional roles in normal and diseased brainForward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signalingSubcellular localization of Patched and Smoothened, the receptors for Sonic hedgehog signaling, in the hippocampal neuronCrosstalk between Notch and Sonic hedgehog signaling in a mouse model of amyotrophic lateral sclerosis.Is my network module preserved and reproducible?Deficiency of patched 1-induced Gli1 signal transduction results in astrogenesis in Swedish mutated APP transgenic miceSonic hedgehog elevates N-myc gene expression in neural stem cells.Hedgehog pathway agonism: therapeutic potential and small-molecule development.The neurogenic effects of exogenous neuropeptide Y: early molecular events and long-lasting effects in the hippocampus of trimethyltin-treated rats.Autism associated gene, engrailed2, and flanking gene levels are altered in post-mortem cerebellum.Prenatal inhibition of the kynurenine pathway leads to structural changes in the hippocampus of adult rat offspring.Interleukin-1β induces blood-brain barrier disruption by downregulating Sonic hedgehog in astrocytes.The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis.The axon-glia unit in white matter stroke: mechanisms of damage and recovery.Opposing roles of voltage-gated Ca2+ channels in neuronal control of regenerative patterning.Altered hippocampal plasticity by prenatal kynurenine administration, kynurenine-3-monoxygenase (KMO) deletion or galantamineComplex oncogenic signaling networks regulate brain tumor-initiating cells and their progenies: pivotal roles of wild-type EGFR, EGFRvIII mutant and hedgehog cascades and novel multitargeted therapies.A Smoothened receptor agonist is neuroprotective and promotes regeneration after ischemic brain injuryLSD1 co-repressor Rcor2 orchestrates neurogenesis in the developing mouse brainNPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200Diet controls Drosophila follicle stem cell proliferation via Hedgehog sequestration and releaseA new syndrome with overlapping features of Townes-brocks syndrome and single median maxillary central incisor syndrome.Hedgehog: Multiple Paths for Multiple Roles in Shaping the Brain and Spinal Cord.Cyclopamine cooperates with EGFR inhibition to deplete stem-like cancer cells in glioblastoma-derived spheroid cultures.Sonic hedgehog, Wnt, and brain-derived neurotrophic factor cell signaling pathway crosstalk: potential therapy for depression.Discovery and evaluation of potential sonic hedgehog signaling pathway inhibitors using pharmacophore modeling and molecular dynamics simulations.NVP-LDE-225 (Erismodegib) inhibits epithelial-mesenchymal transition and human prostate cancer stem cell growth in NOD/SCID IL2Rγ null mice by regulating Bmi-1 and microRNA-128.Genetic activation of Hedgehog signaling unbalances the rate of neural stem cell renewal by increasing symmetric divisions.Prenatal activation of maternal TLR3 receptors by viral-mimetic poly(I:C) modifies GluN2B expression in embryos and sonic hedgehog in offspring in the absence of kynurenine pathway activation.Cerebrospinal fluid from patients with amyotrophic lateral sclerosis inhibits sonic hedgehog function.Disruption of sonic hedgehog signaling in Ellis-van Creveld dwarfism confers protection against bipolar affective disorder.Cell autonomous sonic hedgehog signaling contributes to maintenance of retinal endothelial tight junctions.Green tea epigallocatechin-3-gallate (EGCG) promotes neural progenitor cell proliferation and sonic hedgehog pathway activation during adult hippocampal neurogenesis.Spontaneously regressing brain lesions in Smith-Lemli-Opitz syndrome.
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 10 March 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Sonic Hedgehog signaling in the mammalian brain.
@en
Sonic Hedgehog signaling in the mammalian brain.
@nl
type
label
Sonic Hedgehog signaling in the mammalian brain.
@en
Sonic Hedgehog signaling in the mammalian brain.
@nl
prefLabel
Sonic Hedgehog signaling in the mammalian brain.
@en
Sonic Hedgehog signaling in the mammalian brain.
@nl
P2860
P1476
Sonic Hedgehog signaling in the mammalian brain
@en
P2093
Elodie Angot
Martial Ruat
P2860
P304
P356
10.1111/J.1471-4159.2010.06642.X
P407
P50
P577
2010-03-10T00:00:00Z