NVP-LDE-225 (Erismodegib) inhibits epithelial-mesenchymal transition and human prostate cancer stem cell growth in NOD/SCID IL2Rγ null mice by regulating Bmi-1 and microRNA-128.
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Targeting the Sonic Hedgehog Signaling Pathway: Review of Smoothened and GLI InhibitorsClinical Implications of Hedgehog Pathway Signaling in Prostate CancerCritical roles of miRNA-mediated regulation of TGFβ signalling during mouse cardiogenesis.Combined inhibition of GLI and FLT3 signaling leads to effective anti-leukemic effects in human acute myeloid leukemia.Apoptotic death of cancer stem cells for cancer therapy.Epithelial-mesenchymal transition in prostate cancer: an overview.Inhibition of hedgehog signaling improves the anti-carcinogenic effects of docetaxel in prostate cancer.The androgen receptor plays a suppressive role in epithelial- mesenchymal transition of human prostate cancer stem progenitor cellsmPGES-1 in prostate cancer controls stemness and amplifies epidermal growth factor receptor-driven oncogenicity.PARP Inhibitor PJ34 Suppresses Osteogenic Differentiation in Mouse Mesenchymal Stem Cells by Modulating BMP-2 Signaling PathwaySmall molecule Hedgehog pathway antagonists.PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth.Cancer stem cells and chemoresistance: The smartest survives the raidHedgehog signaling in prostate cancer and its therapeutic implicationα-Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic carcinogenesis by targeting cancer stem cells in human, and transgenic (Kras(G12D), and Kras(G12D)/tp53R270H) mice.Bmi-1 promotes the invasion and migration of colon cancer stem cells through the downregulation of E-cadherin.NUMB inhibition of NOTCH signalling as a therapeutic target in prostate cancer.TRAIL and microRNAs in the treatment of prostate cancer: therapeutic potential and role of nanotechnology.Emerging role of microRNAs in cancer and cancer stem cells.MicroRNA control of epithelial-mesenchymal transition in cancer stem cells.MicroRNAs and drug resistance in prostate cancers.Role of microRNAs in maintaining cancer stem cells.Prostate cancer stem cells: deciphering the origins and pathways involved in prostate tumorigenesis and aggression.Cancer stem cells in prostate cancer.Quinolone-1-(2H)-ones as hedgehog signalling pathway inhibitors.IDH1R¹³²H decreases the proliferation of U87 glioma cells through upregulation of microRNA-128a.Emerging from their burrow: Hedgehog pathway inhibitors for cancer.Cancer-Related Triplets of mRNA-lncRNA-miRNA Revealed by Integrative Network in Uterine Corpus Endometrial Carcinoma.Loss of SNAIL inhibits cellular growth and metabolism through the miR-128-mediated RPS6KB1/HIF-1α/PKM2 signaling pathway in prostate cancer cells.Pharmacodynamic study of the oral hedgehog pathway inhibitor, vismodegib, in patients with metastatic castration-resistant prostate cancer.The Hedgehog-GLI pathway in embryonic development and cancer: implications for pulmonary oncology therapy.Targeted molecular ablation of cancer stem cells for curing gastrointestinal cancers.Hedgehog Pathway Inhibition Hampers Sphere and Holoclone Formation in Rhabdomyosarcoma.miR-128 modulates chemosensitivity and invasion of prostate cancer cells through targeting ZEB1.Immune Curbing of Cancer Stem Cells by CTLs Directed to NANOG.A Role for De Novo Purine Metabolic Enzyme PAICS in Bladder Cancer ProgressionTranscriptomic but not genomic variability confers phenotype of breast cancer stem cells
P2860
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P2860
NVP-LDE-225 (Erismodegib) inhibits epithelial-mesenchymal transition and human prostate cancer stem cell growth in NOD/SCID IL2Rγ null mice by regulating Bmi-1 and microRNA-128.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
NVP-LDE-225 (Erismodegib) inhi ...... lating Bmi-1 and microRNA-128.
@en
type
label
NVP-LDE-225 (Erismodegib) inhi ...... lating Bmi-1 and microRNA-128.
@en
prefLabel
NVP-LDE-225 (Erismodegib) inhi ...... lating Bmi-1 and microRNA-128.
@en
P2093
P2860
P356
P1433
P1476
NVP-LDE-225 (Erismodegib) inhi ...... ulating Bmi-1 and microRNA-128
@en
P2093
P J Van Veldhuizen
R K Srivastava
P2860
P2888
P356
10.1038/ONCSIS.2013.5
P50
P577
2013-04-08T00:00:00Z
P5875
P6179
1047723924