Direct binding of cholesterol to the amyloid precursor protein: An important interaction in lipid-Alzheimer's disease relationships?
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Cholesterol homeostasis: a key to prevent or slow down neurodegenerationOxidized cholesterol as the driving force behind the development of Alzheimer's diseaseStructural and dynamic study of the transmembrane domain of the amyloid precursor proteinRole of berberine in Alzheimer's diseaseThe quiet renaissance of protein nuclear magnetic resonance.Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology.Lipid rafts participate in aberrant degradative autophagic-lysosomal pathway of amyloid-beta peptide in Alzheimer's diseaseMolecular insights into amyloid regulation by membrane cholesterol and sphingolipids: common mechanisms in neurodegenerative diseasesCholesterol in brain disease: sometimes determinant and frequently implicated.Cholestenoic acid, an endogenous cholesterol metabolite, is a potent γ-secretase modulator.Changes in cholesterol metabolism-related gene expression in peripheral blood mononuclear cells from Alzheimer patients.Lipid rafts and Alzheimer's disease: protein-lipid interactions and perturbation of signaling.Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer's disease.Topologically Diverse Human Membrane Proteins Partition to Liquid-Disordered Domains in Phase-Separated Lipid Vesicles.Biochemical identification of a linear cholesterol-binding domain within Alzheimer's β amyloid peptideRegulation of cerebral cholesterol metabolism in Alzheimer disease.Steroids as γ-secretase modulators.Effects of Charged Cholesterol Derivatives on Aβ40 Amyloid Formation.The role of APP proteolytic processing in lipid metabolism.Reciprocal regulation of cholesterol and beta amyloid at the subcellular level in Alzheimer's disease.The link between altered cholesterol metabolism and Alzheimer's disease.Cholesterol as a co-solvent and a ligand for membrane proteins.Lipid rafts in neurodegeneration and neuroprotection.GM1 Ganglioside: Past Studies and Future Potential.Inhibition of Cholesterol Biosynthesis Reduces γ-Secretase Activity and Amyloid-β Generation.Structural and biochemical differences between the Notch and the amyloid precursor protein transmembrane domains.Mechanism of cholesterol-assisted oligomeric channel formation by a short Alzheimer β-amyloid peptide.Amyloid precursor protein and endosomal-lysosomal dysfunction in Alzheimer's disease: inseparable partners in a multifactorial disease.Lipid Rafts: Linking Alzheimer's Amyloid-β Production, Aggregation, and Toxicity at Neuronal MembranesChronic vascular risk factors (cholesterol, homocysteine, ethanol) impair spatial memory, decline cholinergic neurons and induce blood-brain barrier leakage in rats in vivoVascular pathology of 20-month-old hypercholesterolemia mice in comparison to triple-transgenic and APPSwDI Alzheimer's disease mouse models.Effect of surfactant hydrophobicity on the pathway for unfolding of ubiquitin.Competition between homodimerization and cholesterol binding to the C99 domain of the amyloid precursor protein.Look and see if it is time to induce protein expression in Escherichia coli cultures.The impact of cholesterol, DHA, and sphingolipids on Alzheimer's disease.Oxidative stress and the amyloid beta peptide in Alzheimer's disease.The dynamic binding of cholesterol to the multiple sites of C99: as revealed by coarse-grained and all-atom simulations.Cholesterol lowering by Pediococcus acidilactici LAB4 and Lactobacillus plantarum LAB12 in adult zebrafish is associated with improved memory and involves an interplay between npc1l1 and abca1.β-sitosterol inhibits high cholesterol-induced platelet β-amyloid release.The relationship between cholesterol level and Alzheimer's disease-associated APP proteolysis/Aβ metabolism.
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Direct binding of cholesterol to the amyloid precursor protein: An important interaction in lipid-Alzheimer's disease relationships?
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 March 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Direct binding of cholesterol ...... eimer's disease relationships?
@en
Direct binding of cholesterol ...... eimer's disease relationships?
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type
label
Direct binding of cholesterol ...... eimer's disease relationships?
@en
Direct binding of cholesterol ...... eimer's disease relationships?
@nl
prefLabel
Direct binding of cholesterol ...... eimer's disease relationships?
@en
Direct binding of cholesterol ...... eimer's disease relationships?
@nl
P2093
P2860
P1476
Direct binding of cholesterol ...... eimer's disease relationships?
@en
P2093
Andrew J Beel
Charles R Sanders
Masayoshi Sakakura
Paul J Barrett
P2860
P304
P356
10.1016/J.BBALIP.2010.03.008
P407
P577
2010-03-18T00:00:00Z